objective: in previous studies it has been emphasized that the site of morphine action may be either in the embryo or the placenta. in the present study, we attempt to identify the site of morphine action on the fetal section of wistar rat placenta by using c14-morphine. materials and methods: in this study (experimental), female wistar rats (weights: 170-200 g) were mated with male rats and th...

Amiodarone is used in treatment of cardiac arrhythmias. Therapeutic use of amiodarone is limited by its side effects, including pulmonary toxicity. Human Placenta Extract (HPE) contains a variety of bio-active substances. Thus, the present study aimed to quantitatively evaluate the protective effects of HPE on the structural lung changes induced by amiodarone using stereological methods. Spragu...

Amiodarone is used in treatment of cardiac arrhythmias. Therapeutic use of amiodarone is limited by its side effects, including pulmonary toxicity. Human Placenta Extract (HPE) contains a variety of bio-active substances. Thus, the present study aimed to quantitatively evaluate the protective effects of HPE on the structural lung changes induced by amiodarone using stereological methods. Spragu...

Introduction: To attach the fetus to the endometrial epithelium, the endometrium should be affected and allowed by the steroid hormones secreted from the ovary. Thus, the endometrium is then subject to several structural and biochemical changes. Implantation involves the embedment, adhesion and invasion steps that specific receptors are engaged in that. The role of membrane receptors in uterine...

The placental adhesive disorders such as placenta accreta and placenta percreta are the rare causes of serious obstetric hemorrhages. They are associated with high maternal morbidity and mortality. Placenta percreta is usually diagnosed in the third trimester of pregnancy as a massive postpartum hemorrhage when an attempt to remove the placenta reveals lack of a cleavage plane. Here we report a...

Background and aim: Horseshoe placenta is a variant of ring-shaped placenta. Ring-shaped placenta is a rare anomaly seen in fewer than 1 in 6000 deliveries, which could be seen as horseshoe shape due to atrophy in a portion of the ring. This report refers to a possible relationship between the horseshoe shape placenta and preterm labor; although it has not been yet validated in the literature. ...

background: placenta accreta is a rare obstetrical condition that mainly occurs in the third trimester leading to life-threatening complications. hereby, a case of uterine rupture due to placenta accreta occuring in the second trimester is presented. case presentation: a forty-year old patient who conceived after in vitro fertilization treatment (oocyte donation and embryo transfer) presented i...

objective: carthamus tinctorius l. (safflower) is a member of the asteraceae family which is used as a food additive but also has medicinal applications. this study investigated its effects on placental histomorphology and survival of mice neonates. materials and methods: eighty balb/c pregnant mice were randomly distributed into one control and three experimental groups (n=20). the control gro...