نتایج جستجو برای: pldh

تعداد نتایج: 124  

2013
Mélanie Trouvay Georges Palazon Franck Berger Béatrice Volney Denis Blanchet Emilie Faway Damien Donato Eric Legrand Bernard Carme Lise Musset

BACKGROUND Care for malaria patients in endemic areas has been improved through the increasing use of Rapid Diagnostic Tests (RDTs). Most RDTs target the histidine-rich protein-2 antigen (PfHRP2) to detect P. falciparum, as it is abundant and shows great heat stability. However, their use in South America has been widely questioned following a recent publication that pinpoints the high prevalen...

Journal: :Journal of tropical pediatrics 2008
Sikirat A Sotimehin Tamrat I Runsewe-Abiodun Olufemi T Oladapo Olisamedua F Njokanma Duro M Olanrewaju

Congenital malaria, defined as the presence of malaria parasites in the erythrocytes of newborns aged <7 days, was considered rare in endemic areas until recent studies started reporting high prevalence rates. Various theories have been postulated to explain this phenomenon, but they are not proven conclusively from research. Against this background, a prospective study was designed with the fo...

2013
Priyanka Verma Sukla Biswas Teena Mohan Shakir Ali D.N. Rao

BACKGROUND & OBJECTIVES Despite major control efforts, malaria remains a major public health problem that still causes high mortality rate worldwide especially in Africa and Asia. Accurate and confirmatory diagnosis before treatment initiation is the only way to control the disease. The present study was undertaken to develop reagents using sandwich ELISA for simultaneous detection of PfHRP2 (P...

Journal: :Journal of clinical microbiology 2010
Sharon Wein Marjorie Maynadier Christophe Tran Van Ba Rachel Cerdan Suzanne Peyrottes Laurent Fraisse Henri Vial

In vitro antimalarial activity tests play a pivotal role in malaria drug research or for monitoring drug resistance in field isolates. We applied two isotopic tests, two enzyme-linked immunosorbent assays (ELISA) and the SYBR green I fluorescence-based assay, to test artesunate and chloroquine, the metabolic inhibitors atovaquone and pyrimethamine, our fast-acting choline analog T3/SAR97276, an...

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