Objectives- The purpose of the study was to observe whether PRP, Mesenchymal Stem Cells (MSCs) and combining them could help make improvements the healing of Achilles tendons in rabbits. Design- Experimental study. Animals-Sixteen male, healthy and mature white New Zealand rabbits. Procedures- The animals were...

autologous fat transfer offers many qualities of a ideal soft tissue filler. main advantages of fat grafting ensue from the fact that the lipoaspirate tissue is an abundant source of regenerative pluripotential cells. however, the reported rates of fat cell survival vary greatly in the medical literature (10-90%). different techniques of harvesting, processing, and reinjecting the fat cells are...

conclusions it seems that applying prp is an effective therapeutic approach for wound healing, and faster wound healing is expected due to the presence of more platelets and growth factors. results at the end of study, the prp group showed a greater reduction in the edema ecchymosed discharge approximation (reeda) score compared to the control group (85.5% reduction in the prp group; 72% in the...

objective(s): platelet-rich plasma (prp) has recently emerged as a promising strategy in regenerative medicine due to its multiple endogenous growth factors. little is known about the role of prp as a promoter in chondrogenesis of human adipose derived stem cells (hadscs). the aim of this study was to determine whether prp may be considered as a natural and easy achievable source of growth fact...

C-reactive protein is the prototypic acute phase reactant. A self-complexed form (H-CRP) can induce isolated platelets to undergo aggregation, secretion of dense and alpha-granule constituents, and generation of thromboxane A2, but fails to function in platelet-rich plasma (PRP) as a direct agonist. In contrast, when PRP was activated with an amount of adenosine diphosphate (ADP) that produced ...

The first glycoconjugate vaccine using isolated glycans was licensed to protect children from Haemophilus influenzae serotype b (Hib) infections. Subsequently, the first semisynthetic glycoconjugate vaccine using a mixture of antigens derived by polymerization targeted the same pathogen. Still, a detailed understanding concerning the correlation between oligosaccharide chain length and the immu...

Circumscribed juvenile pityriasis rubra pilaris (PRP) is a form of PRP that manifests with well-defined erythematous scaly plaques with follicular keratosis mainly over knees and elbows. There are several reports of the association of PRP with other conditions. We report a boy with scattered erythematosquamous skin lesions and follicular hyperkeratotic papules since the age of six years. ...

PURPOSE This study investigates the antibacterial properties of two different platelet-rich plasma (PRP) platelet concentration preparations (PRPLP and PRPHP) through a time-kill assay. METHODS Two different PRP preparations - a single spin process yielding lower white blood cells and platelet concentration (PRPLP) and one yielding high platelet and white blood cell concentration (PRPHP) - we...

BACKGROUND Platelet-rich plasma (PRP) contains multiple growth hormones that may stimulate tissue repair. This study aimed to assess the effects of PRP in a rabbit model of IDD (annulus fibrosus puncture). MATERIAL/METHODS Thirty-six adult New Zealand white rabbits were randomly divided into 3 groups: 0.1 mL PRP (group A), 0.1 mL phosphate-buffered saline (group B), and control (group C) (n=1...