..................................................................................................... 4 List of publications .................................................................................... 6 Abbreviations ............................................................................................. 7 Introduction .................................................................

Combined rupture of Reissner's membrane and the round window membrane (double-membrane rupture) as a cause of acute profound sensorineural hearing loss was investigated in guinea pigs. Action potentials (APs) of the cochlear nerve in response to tone pip stimuli (1, 2, 4, 8kHz) were recorded before and after rupture of Reissner's membrane at each turn of the cochlea. Then the round window was p...

Background: To determine maternal risk factors and perinatal outcomes of preterm births in south-western Nigeria. Methods: A retrospective study of preterm and term deliveries in a tertiary hospital in Nigeria. The delivery records were reviewed and case files of preterm births were identified and retrieved. Perinatal outcomes were determined by review of the postnatal and special care baby uni...

This study aims to explore potential clinical relevance of sHLA-G to premature rupture of membrane. 75 samples of pregnancy were enrolled, including patients with preterm premature rupture of membranes (PPROM), patients with term premature rupture of membranes (TPROM) and normal pregnancy women. Level of sHLA-G in multiple sites were examined with ELISA. Lymphocytes were isolated from periphera...

The fetal membrane surrounds the fetus during pregnancy and is a thin tissue composed of two layers, the chorion and the amnion. While rupture of this membrane normally occurs at term, preterm rupture can result in increased risk of fetal mortality and morbidity, as well as danger of infection in the mother. Although structural changes have been observed in the membrane in such cases, the mecha...