Lateral Ankle sprain (LAS) is a common sports injury associated with recurrent ankle sprain, chronic ankle instability(CAI) and post-traumatic ankle osteoarthritis (PTOA). Platelet Rich Plasma (PRP) has been increasingly used forherapeutic applications in sports-related injuries, and is thought to stimulate tissue healing. We reported a case ofLAS with complete tear of anterior talofibular liga...

conclusions both l-prp and l-prf could be used to effectively promote the healing of articular cartilage defects of the knee. results mean macroscopic scores of the treated defects were higher than the controls at all sampling times with significant differences (p < 0.05) observed between l-prf treated and control defects (10.13 vs. 8.37) and l-prp treated and control defects (10 vs. 8.5) at 4 ...

autologous fat transfer offers many qualities of a ideal soft tissue filler. main advantages of fat grafting ensue from the fact that the lipoaspirate tissue is an abundant source of regenerative pluripotential cells. however, the reported rates of fat cell survival vary greatly in the medical literature (10-90%). different techniques of harvesting, processing, and reinjecting the fat cells are...

BACKGROUND Platelet-rich plasma (PRP) can provide an assortment of growth factors, but how PRP effects bone regeneration is still unknown. The aim of the study was to explore an optimal method of using PRP and bone marrow stromal cells (BMSCs). METHODS An in vitro experiment was first conducted to determine an appropriate quantity of PRP. BMSCs were cultured with PRP of different concentratio...

The treatment of solitary bone cysts remains controversial. The high recurrence rate after operative treatment calls for the search of new effective treatment methods. The aim of this study was to evaluate the outcomes of treatment of solitary bone cysts with platelet-rich plasma (PRP) and allogenic bone grafts. The study group consisted of 9 patients (4 males and 5 females) with the diagnosis ...

Bleeding time, platelet retention on glass beads, and ristocetin-induced platelet agglutination (RIPA) in platelet-rich plasma were simultaneously determined for 20 patients with chronic renal failure and previous hemorrhagic history. In seven patients chosen at random out of a group of 16 in whom the three tests were abnormal, RIPA of uremic-isolated platelets in presence of normal platelet-po...

Platelet concentrates for surgical use are autogenous regenerative preparations, produced by the centrifugation of the patient own blood sample. Most techniques are often regrouped inappropriately under the historical term of Platelet-Rich Plasma (PRP). Since 15 years, their use dramatically increased in many surgical fields, particularly in oral and maxillofacial surgery. The literature on thi...

Background: The purpose of this study was to create biomaterial scaffolds like platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) containing stromal cell-derived factor-1 (SDF1) as a chemokine to induce hyaline cartilage regeneration of rabbit knee in a full thickness defect.Methods: We created a full thickness defect in the trochlear groove of thirty-six bilateral knees of eighteen matu...

objective(s): platelet-rich plasma (prp) has recently emerged as a promising strategy in regenerative medicine due to its multiple endogenous growth factors. little is known about the role of prp as a promoter in chondrogenesis of human adipose derived stem cells (hadscs). the aim of this study was to determine whether prp may be considered as a natural and easy achievable source of growth fact...