altan derivatives of polycyclic conjugated hydrocarbons were recently introduced and studied in theoretical organic chemistry. we now provide a generalization of the altan concept, applicable to any graph. several earlier noticed topological properties of altan derivatives of polycyclic conjugated hydrocarbons are shown to be the properties of all altan derivatives of all graphs. among these ar...

Phenylazo and benzothiazolylazo derivatives of trifluoroacetylacetone andhexafluoroacetylacetone have been synthesized and characterized. Analytical and spectral datarevealed the existence of phenylazo derivatives in the intramolecularly hydrogen-bonded ketohydrazoneform while the benzothiazolylazo derivatives in the azo-enol form. The monobasicbidentate coordination of the phenylazo derivative...

there has been special interest in the chemistry of quinolone and pyrimidine derivatives due to their diverse biological activities such as anticonvulsant, anti-malarial agents, antibacterial, antiviral, cytostatic, antithelemintic, antigenotoxic, anti-cancer agents. these compounds are also used as targeting delayed-type hypersensivity and anti-convulsant agents. as a part of our research work...

some n¬-acyl-n'-aryl thiourea derivatives 4(a-f) have been prepared by the reaction of acyl halides ammonium thiocyanate and aryl amines. the structures of synthesized compounds have been characterized by ir, 1hnmr spectral studies. the synthesized compounds 5(a-f) have been screened for antibacterial activity. the effect of the structure of the investigated compounds on the antibacterial ...

objective(s) anxiety is a common disorder which afflicts many people in any society and is often accompanied by physiological sensations such as tachycardia, chest pain, shortness of breath, insensitivity, etc. the purpose of present study was to evaluate the putative anxiolytic-like effects of phencyclidine ('-('-phenylcyclohexyl) piperidine, cas 956-90-1, pcp, i) and its methyl and ...

A series of cyclic analogues of bioactive thiosemicarbazide derivatives have been synthesized as potential antimycobacterial agents. The 4-amino-1,2,4-triazole-5-thione analogues (Ia-f) were prepared by heating a mixture of thiocarbohydrzide and appropriate carboxylic acids. Reaction of thiocarbohydrazide with γ-ketoesters in the presence of sodium methoxide furnished triazolopyridazine derivat...

A series of cyclic analogues of bioactive thiosemicarbazide derivatives have been synthesized as potential antimycobacterial agents. The 4-amino-1,2,4-triazole-5-thione analogues (Ia-f) were prepared by heating a mixture of thiocarbohydrzide and appropriate carboxylic acids. Reaction of thiocarbohydrazide with γ-ketoesters in the presence of sodium methoxide furnished triazolopyridazine derivat...

Utilization of benzoxazinone for synthesis quinazolinone derivatives with 3-heterocycle side chain. treatment of benzoxazinon 1 with cyano acetohydrazide or thionocarbohydrazide gave the quinazolinone derivatives 2 or 12. quinazolinone 2 has been utilized as synthon for new  pyridinone, oxazet, thiazole, thiazolidinone and quinazolinone derivatives. Thiosemicarbazide and thiosemicarbazone deriv...