In the developing vertebrate hindbrain Hoxa1 and Hoxb1 play important roles in patterning segmental units (rhombomeres). In this study, genetic analysis of double mutants demonstrates that both Hoxa1 and Hoxb1 participate in the establishment and maintenance of Hoxb1 expression in rhombomere 4 through auto- and para-regulatory interactions. The generation of a targeted mutation in a Hoxb1 3' re...

We model membrane proteins as anisotropic objects characterized by symmetric-traceless tensors and determine the coupling between these orderparameters and membrane curvature. We consider the interactions 1) between transmembrane proteins that respect up-down (reflection) symmetry of bilayer membranes and that have circular or non-circular cross-sectional areas in the tangent-plane of membranes...

Objectives. To validate the Schizophrenia Quality of Life Scale Revision 4 (SQLS-R4) Chinese version with factor analysis. We also investigated factors influencing quality of life results. Method. One hundred patients with schizophrenia participated in this study. Experienced psychiatrists evaluated each patient's current psychological condition to assure intact judgment. Participants then fill...

The tectofugal system of the pigeon was examined for the distribution of several glutamate-receptor subunits (AMPA Glu R1, Glu R2/3, Glu R4) and the calcium binding protein parvalbumin. With respect to the different antigens, a heterogeneous distribution was observed. Within the optic tectum, the Glu R1 like immunoreactivity was limited to the layers 2-5, 9, 10, and sparsely in layer 13, wherea...

The tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) is a potent inducer of apoptosis in many cancer cells. However, a significant proportion of tumours are TRAIL-resistant erecting a major hurdle for a successful TRAIL-based treatment regimen in the future. In this context, it would be a major advantage to be able to identify the tumours that respond to TRAIL. The existence of ...

conclusions thoracoscopic sympathicotomy shows proper results in treatment of phh. thoracoscopic r3-r5 sympathicotomy compared with r2-r4 sympathicotomy is a preferable method, because of similar results and fewer complications. objectives this study was planned to evaluate and compare complications and patients’ satisfaction of thoracoscopic sympathicotomy in levels of r2-r4 versus r3-r5 for p...

The current study aimed to evaluate the impact of charcoal grilling in generation various polycyclic aromatic hydrocarbons tissues 5 different organs (leg, chest, wings, liver, and heart) falcated ducks ( Mareca falcata) before after pasting them with condiment recipes (R1, R2, R3, R4). All condiment-pasted control samples before/after were pursued RP-HPLC for quantification unknown PAHs. Tissu...

The unique t(15;17) of acute promyelocytic leukemia (APL) fuses the PML gene with the retinoic acid receptor alpha (RAR alpha) gene. Although retinoic acid (RA) inhibits cell growth and induces differentiation in human APL cells, resistance to RA develops both in vitro and in patients. We have developed RA-resistant subclones of the human APL cell line, NB4, whose nuclear extracts display alter...

OBJECTIVES Outcomes of casualties with thoracic wounding at the deployed UK military field hospital (Role 3(R3)) have been previously described. The level of cardiothoracic specialist input required on repatriation to the UK is less clear. This study aimed to assess the outcomes of casualties with thoracic injuries repatriated to the UK (Role 4 (R4)) and evaluate the impact of specialist cardio...