Subject-specific musculoskeletal modelling is especially useful in the study of juvenile and pathological subjects. However, such methodologies typically require a human operator to identify key landmarks from medical imaging data and are thus affected by unavoidable variability in the parameters defined and subsequent model predictions. The aim of this study was to thus quantify the inter- and...

Background High repeatability, accuracy, and precision for renal function measurements need to be achieved to establish renal dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) as a clinically useful diagnostic tool. Purpose To investigate the repeatability, accuracy, and precision of DCE-MRI measured renal perfusion and glomerular filtration rate (GFR) using iohexol-GFR as the refe...

The development of strategies to combat hepatic disease and augment tissue regeneration has created a need for methods to assess regional liver function. Liver perfusion imaging has the potential to fulfil this need, across a range of hepatic diseases, alongside the assessment of therapeutic response. In this study, the feasibility of hepatic arterial spin labelling (HASL) was assessed for the ...

OBJECTIVE To evaluate the stability and repeatability of measures of mechanical (nociceptive) thresholds in piglets and to examine potentially confounding factors when using a hand held algometer. STUDY DESIGN Descriptive, prospective cohort. ANIMALS Forty-four piglets from four litters, weighing 4.6 ± 1.0 kg (mean ± SD) at 2 weeks of age. METHODS Mechanical thresholds were measured twice...

Background and Aims: The accurate mechanisms of ankle instability cannot be assessed in the absence of reliable knowledge about ground reaction force (GRF) variables. The purpose of this study was to evaluate the test-retest reliability of GRF variables during forward and lateral jump-landing in volleyball players with functional ankle instability (FAI). Methods: Eighteen professional volle...

BACKGROUND The difference between the postpacing interval (PPI) and the tachycardia cycle length (TCL; PPI-TCL) is a useful tool in mapping macro-reentrant tachycardias. However, entrainment pacing causes some perturbation of the conduction velocity within the tachycardia circuit, which may affect the repeatability and consequently the accuracy of the measurement of PPI-TCL. The aim of this stu...

The aim of this study was to investigate intra- and interspecimen repeatability of an experimental procedure, which determines elastic and viscoelastic properties of knee ligaments. The collateral ligaments from sheep were used and the repeatability was evaluated in terms of the coefficient of variation. The results indicated a good intraspecimen repeatability (the coefficient of variation gene...

Cerebrovascular reactivity (CVR) can be mapped using BOLD fMRI to provide a clinical insight into vascular health that can be used to diagnose cerebrovascular disease. Breath-holds are a readily accessible method for producing the required arterial CO2 increases but their implementation into clinical studies is limited by concerns that patients will demonstrate highly variable performance of br...

Knowledge and control of residual strain is critical for device design in MEMS, and therefore it is important to establish standards for residual strain measurement. In this study, pointer, microring, bent-beam, and fixed-fixed beam test structures are used to evaluate residual strain both theoretically and experimentally. An equation that enables easier evaluation of bentbeam structures is der...

PURPOSE We assessed the repeatability and reproducibility of abutment teeth dental impressions, digitized with a blue light scanner, by comparing the discrepancies in repeatability and reproducibility values for different types of abutment teeth. MATERIALS AND METHODS To evaluate repeatability, impressions of the canine, first premolar, and first molar, prepared for ceramic crowns, were repea...