conclusions the frequency of rls among our patients was remarkable and we conclude that all patients who are undergoing hemodialysis should be screened for rls, which can assist in providing proper attention and treatment. results according to our results, 54.5% of patients were diagnosed with rls, and of those 65.2% and 42.9% were women and men, respectively. rls is seen more often among patie...

BACKGROUND The aim of this study was to determine the reliability, validity and responsiveness of the Restless Legs Syndrome Quality of Life questionnaire (RLSQoL) in a clinical trial setting. METHODS Two matching, placebo-controlled, multinational studies assessing the effectiveness and safety of ropinirole for treating moderate-to-severe Restless Legs Syndrome (RLS) formed the basis of this...

Restless legs syndrome (RLS) is characterised by daily dynamic sensorial and motor syndromes. It is a relatively little known syndrome among neurologists as well as psychiatrists. In spite of a growing number of researches on this issue, the problem seems to be underdiagnosed. Because of a subjective character of the symptoms and also their appearance in the evening hours, they are difficult to...

Introduction: Restless Legs Syndrome (RLS) is a sensorimotor disorder with a prevalence of 5-10% in western countries [1]. The disorder is characterized by uncomfortable leg sensations with an irresistible urge to move the legs, causing chronic sleep disruption at night. Evidence from a number of analytical approaches has suggested that insufficient brain iron may underlie the pathophysiology o...

Historically, epidemiological studies of restless legs syndrome (RLS) have been limited by the subjective nature of the disease, the lack of standardized diagnostic criteria, and the sometimes indolent onset of the condition. Ekbom initially estimated a 5% prevalence of RLS in the general population [1]. Subsequent general population surveys by Strang [2] and Cirignotta [3] demonstrated prevale...

OBJECTIVES To evaluate the association between restless legs syndrome (RLS) and incident cardiovascular disease (CVD). DESIGN Prospective cohort study. SETTING Women's Health Study (WHS) and Physicians' Health Study (PHS), USA. PARTICIPANTS 29 756 female health professionals aged ≥45 years and 19 182 male physicians aged ≥40 years at baseline. MAIN OUTCOME MEASURES Main outcome was inci...

Opioids have been shown to provide symptomatic relief from dysaesthesias and motor symptoms in restless legs syndrome (RLS). However, the mechanisms by which endogenous opioids contribute to the pathophysiology of RLS remain unknown. We have studied opioid receptor availability in 15 patients with primary RLS and 12 age-matched healthy volunteers using PET and [11C]diprenorphine, a non-selectiv...

High prolactin hormone level in the blood is known as hyperprolactinemia. The most common symptom of hyperprolactinemia is galactorrhea, in which spontaneous milky discharge is seen from all ducts of the two mammary glands. Dopamine has an inhibitor effect on prolactin, in the tuberoinfundibular tract and inhibition of dopamine increases the serum prolactin level (Feuchtl et al. 2004). Monoamin...