introdouction: mucoepidermoid carcinoma (mec) is one of the most common salivary gland malignancies. the prevalence of salivary gland tumors varies in different geographic areas. in this report, we evaluated the prevalence of mec in iran and compared it with that previously reported in other countries. materials and methods: the files of oral pathology, shahid beheshti university of medical sci...

with poor prognosis, rapid growth, distant metastasis, early regional metastasis, and a high rate of recurrence. The parotid gland is the most common site of involvement, and the lungs and the bones are the most common sites of distant metastasis of SDC. Herein, we present a case of SDC of the parotid gland in a 62-year-old male patient with an unusual metastasis to the skin of the primary site...

Normal salivary gland tissue has been recognized to positively stain for PSA, independently of gender, while immunostaining for AR has not been consistently found [6, 7]. Immunostaining for AR, and occasionally for prostatic acid phosphatase and PSA, has been reported in duct carcinoma and adenocarcinoma of salivary glands in both sexes [3–6, 8]. These findings suggest that, unlike prostate can...

background and aims. various morphologies are seen in different salivary gland tumorsor within an individual tumor, and the lesions show divers biological behaviors. experimental results support the hypothesis that increased crkii proto-oncogene is associated with cytokine-induced tumor initiation and progression by altering cell motility signaling pathway. the aim of this study was to assess t...

Accidental discovery of androgen receptor (AR) expression in high-grade salivary gland cancer led to evaluation of that finding. In this study we evaluated the immunohistochemical expression of AR in a series of 37 formalin-fixed, paraffin-embedded malignant salivary gland tumors using two commercially available antibodies. Nuclear immunoreactivity for AR was demonstrated in 3 of 4 salivary duc...

A case of concurrent preputial calculi and carcinoma of the penis is reported. The causal relationship of both the lesions is still controversial and the possible common aetiopathogenesis of the entity is discussed.

Human kallikrein 6 (hK6), also known as zyme/protease M/neurosin), is expressed in many normal glandular tissues. The aim of this study was to determine whether hK6 is expressed in salivary gland tissues and salivary gland tumors (both benign and malignant), using an immunohistochemical method. Pleomorphic adenomas (PA), adenoid cystic carcinomas, polymorphous low-grade adenocarcinomas, acinic ...

BACKGROUND Salivary ductal carcinoma and carcinoma ex pleomorphic adenoma (CEPA) are aggressive salivary gland cancers with poor prognosis. The standard of care is resection with or without radiotherapy, and there are no established systemic therapy options. METHODS We describe 1 patient with metastatic CEPA and 1 patient with metastatic recurrent salivary duct carcinoma whose tumors were eva...