As a chronic psychiatric disorder, schizophrenia affects the worldwide population with a lifetime prevalence of 1% and considerable long-term mortality, morbidity, and burden. Besides the adverse effects of routine treatment regimens, a significant portion of patients remain symptomatic despite treatment, especially those with negative symptoms which are the major disabling factors in these pat...

Lycanthropy is an unusual belief or delusion in which the patient thinks that he/she has been transformed into an animal. In rare cases, the patient believes that another person has been transformed into an animal. In this case report, a patient who had an uncommon variant of lycanthropy is introduced. The patient’s symptoms had appeared after consumption of ecstasy. This shows the occurrence o...

Objectives: The purpose of this study was to investigate the effect token economy intervention on clinical characteristics and global function patients with schizophrenia.Methods: From June 1, 2022 September 2022, conducted for hospitalized schizophrenia in a mental hospital. Assessments were before after intervention. Clinical Global Impression-Schizophrenia scale (CGI-SCH), Schizophrenia Qual...

objectives: against the background of evidence-based treatments for schizophrenia resistant to medication, the implementation of cognitive-rehabilitation therapy (crt) becomes more important, especially about patients who don’t response to medication. there is less evidence for group format and face to face structure of crt and also for resistant to medication patients. this research investigat...

impact of psychoeducational groups for caregivers on the psychiatric symptoms of patients with schizophrenia     shaygan m [1] *, sharif f [2]     received: 21 nov, 2012 accepted: 11 feb , 2013     abstract:   background & aims : schizophrenia is a severe psychiatric disorder, which is extremely stressful not only for the persons affected but also for their families.   materials & methods : to ...

Schizophrenia is a chronic and often debilitating illness which affects about 1% of the world population. Some reagents have been used to simulate schizophrenic disorders in laboratory animals, such as amphetamine and ketamine. Previous studies have suggested that reactive oxygen species (ROS) production, reduced levels of ATP, mitochondrial dysfunction and apoptosis are involved in the pathoph...

Persons with schizophrenia have higher rates of cardiovascular disease and exhibit inflammatory abnormalities. Emerging evidence has linked the gut microbiome changes to schizophrenia. However, there been limited research into functional pathways by which microbiota contributes phenotype persons chronic

Introduction: Patients with schizophrenia characteristically exhibit cognitive deficits. The level of cognitive impairment is found to predict the functional outcome of the illness more strongly than the severity of positive or negative symptoms. The purpose of this study was to assess the efficacy of ondansetron, a 5-HT3 receptor antagonist as an adjuvant agent in the treatment of chronic...