Sequence comparison has been widely used in many engineering systems, such as fuzzy keyword search, plagiarism detection, and comparison of gene sequences. However, when the length of the string is extraordinarily long, like the DNA sequence that contains millions of nucleotides, sequence comparison becomes an intractable work, especially when the DNA database is big and the computation resourc...

paris polyphylla smith var. yunnanensis (liliaceae) is an important traditional medicinal plant of the yunnan province in china. however, the genomic information regarding this plant is limited. to further understand its molecular background, we conducted illumina hiseq 2000 second-generation sequencing of this plant species. approximately 30,198,679 reads with an average length of 202 bases we...

background: malassezia are dimorphic, lipid-dependent yeasts, which are responsible for causing several cutaneous and sys­temic conditions. although cyclophilins (cyps) are highly conserved cytosolic proteins that catalyze the peptidyl-prolyl cis-trans isomerazation reaction before protein folding process, it has been suggestive of an allergen in a few numbers of fungi such as aspergillus fumig...

mycoplasma synoviae expressed variable lipoprotein haemagglutinin (vlha) is believed to play a major role in pathogenesis of the disease by mediating adherence and immune evasion. the aim of this study was sequencing iranian m. synoviae isolates for the detection of nucleotide variation in the m. synoviae vlha gene. using oligonucleotide primers complementary to the single-copy conserved 5´ end...

purpose: suitable magnetic resonance imaging (mri) techniques from conventional to new devices can help physicians in diagnosis and follow up of multiple sclerosis (ms) patients. the aim of present research was to compare effectiveness of fluid attenuation inversion recovery (flair) sequence of conventional mri and diffuse weighted imaging (dwi) sequence as a new technique in detection of brain...

The wealth of protein sequence and structure data is greater than ever, thanks to the ongoing Genomics and Structural Genomics projects. The information available through such efforts needs to be analysed by new methods that combine both databases. One important result of genomic sequence analysis is the inference of functional homology among proteins. Until recently sequence similarity compari...