How do biochemical signaling pathways generate biological specificity? This question is fundamental to modern biology, and its enigma has been accentuated by the discovery that most proteins in signaling networks serve multifunctional roles. An answer to this question may lie in analyzing network properties rather than individual traits of proteins in order to elucidate design principles of bio...

This paper examines the potential and the impact of introducing learning capabilities into autonomous agents that make decisions at run-time about which mechanism to exploit in order to coordinate their activities. Specifically, the efficacy of learning is evaluated for making the decisions that are involved in determining when and how to coordinate. Our motivating hypothesis is that to deal wi...

The American cultural imaginary is hungry for death, and thus representations of death are prominently repeated serialized in US literature media. Stella Castelli shows how culture fetishizes as part a repetition compulsion which stems from the inability language to satisfactorily grasp death. Taking an intermedial approach, she investigates forms tropes born this preoccupation with conceptuali...

abstract parasitic insects face many decisions when foraging for host, some for example frequently have to make decisions with regard to staying in or leaving their current patch. in this study, we investigated how the foraging and oviposition behavior of lysiphlebus fabarum is influenced by (1) a female’s previous experience of encountering aphids host and (2) age of female parasitoids. to tes...

Designing complex systems requires collaboration among multiple engineers who coordinate to plan tasks, cooperate to resolve dependencies, and co-construct to identify shared objectives and solutions. While collaboration technologies have been developed to date, few can help designers negotiate effectively and reach agreement efficiently. In this paper, we propose an argumentation based enginee...

This paper investigates the impacts of and incentives towards vertical integration or separation between an infrastructure manager and a network operator when downstream services may require the access to multiple networks. We show that returns-to-scale and the intensity of competition in the final markets are key to understanding the impact of vertical integration in this context. We also disc...

abstract the decisions and personal preferences of the designer are vital for all aspects and stages of the design. to elaborate, the designer has the central role in creation, development, detailing and construction of the built forms. also, the scientific/engineering evaluations of the design models are carried out under the directions and decisions of the designer. the paper explores the con...