Takotsubo cardiomyopathy is a rare type of nonischemic cardiomyopathy accompanied by a transient ballooning and akinesis of the apical segment of left ventricle. Here, we report a 28-year-old woman who presented with acute chest pain after an emotional stress. Electrocardiography showed STsegment elevation in leads II, III, aVF, V3-V6. Echocardiography, coronary angiography and left ventriculog...

AIMS Regulatory proteins of the sarcomere are pivotal for normal heart function and when affected by mutations are frequently causing cardiomyopathy. The exact function of these regulatory proteins and how mutations in these translate into distinct cardiomyopathy phenotypes remains poorly understood. Mutations in the essential myosin light chain (ELC) are linked to human cardiomyopathy characte...

Introduction. Stress cardiomyopathy, or takotsubo cardiomyopathy, is an acute, reversible left ventricular dysfunction usually initiated by a psychological or physical stress. We report this case of stress cardiomyopathy following a chronic obstructive pulmonary disease exacerbation and the subsequent treatment. Case Description. A 49-year-old white female with a history of chronic obstructive ...

the chronic stage was extensive and showed septal predominance (Figure). These findings are consistent with those described in myocarditis series, which would indicate a common pathophysiological process for both entities. Gadolinium late-enhancement would indicate an increase of inflammatory activity in this condition. Although similar findings have been observed in patients with dilated cardi...

[This corrects the article on p. 527 in vol. 8, PMID: 28496419.].

The endoplasmic reticulum (ER) is an organelle entrusted with lipid synthesis, calcium homeostasis, protein folding, and maturation. Perturbation of ER-associated functions results in an evolutionarily conserved cell stress response, the unfolded protein response (UPR) that is also called ER stress. ER stress is aimed initially at compensating for damage but can eventually trigger cell death if...

Acute stress cardiomyopathy is the unique disease which represents exaggerated and dysfunctional regions of the same cardiac tissue at the same episode. The impressive clinical course which involves the specific region is the stress-mediated exaggerated function of LV base under acutely developed stress induction. After abolishment of stress induction, dysfunctional part of LV which is the mida...

background: serum trace element alteration has been reported in dilated and ischemic cardiomyopathy. the reports were controversial. we have studied serum zinc level in cardiomyopathy patients in northern province of mazandaran and compared them with healthy volunteers. methods: serum zinc level was measured in 30 ischemic and 18 dilated cardiomyopathy patients against 27 healthy volunteers. it...