Little is known about the role of class 3 semaphorins in the development of CNS circuitry. Several class 3 semaphorins, including semaphorin 3F (Sema3F) bind to the receptor neuropilin-2 to confer chemorepulsive responses in vitro. To understand the role of Sema3F in the establishment of neural circuitry in vivo, we have generated sema3F null and sema3F conditional mutant mice. Inspection of th...

The semaphorins are a large family of secreted or cell-bound signals needed for the development of the nervous system. We compared mRNA expression of class 3 semaphorins (Sema3A, 3B, 3C and 3F) and their two receptors (Neuropilin-1 and -2) in the embryonic mouse first molar tooth germ (E10-18) by radioactive in situ hybridization. All genes showed distinct developmentally regulated expression p...

Stroke merupakan suatu kondisi klinis yang dapat menyebabkan menurunnya fungsi saraf dipengaruhi oleh cidera pada system pusat. tingginya angka kematian dan kecacatan. Pemeriksaan awal secara tepat cermat merupan tindakan berpengaruh penatalaksanaan. Terdapat alat bantu skoring digunakan dalam membantu menegakkan diagnosa memprediksi jenis stroke apabila di IGD rumah sakit belum tersedia standa...

This paper explores the deterministic transistor reordering in low-voltage dynamic BiCMOS logic gates, for reducing the dynamic power dissipation. The constraints of load driving (discharging) capability and NPN turn-on delay for MOSFET reordered structures has been carefully considered. Simulations shows significant reduction in the dynamic power dissipation for the transistor reordered BiCMOS...

The mechanisms that underlie axonal pathfinding of vomeronasal neurons from the vomeronasal organ (VNO) in the periphery to select glomeruli in the accessory olfactory bulb (AOB) are not well understood. Neuropilin-2, a receptor for secreted semaphorins, is expressed in V1R- and V3R-expressing, but not V2R-expressing, postnatal vomeronasal neurons. Analysis of the vomeronasal nerve in neuropili...

”. It is shown that in order to increase the efficiency of functioning complete logistical supply chains (CLSC), it necessary develop special methodological tools, and, on their basis, software facilitate decision-making timely formation liquid consignments at terminal sections chain goods. The article describes a fuzzy network CLSC form hierarchical two-level nested Petri net (NPN), upper leve...

Five ruminally and duodenally cannulated steers (491 +/- 21 kg BW) were used in an incomplete 5 x 4 Latin square with four 24-d periods to determine the influence of supplemental nonprotein N (NPN) source and supplementation frequency (SF) on the dynamics of ruminal fermentation in steers consuming low-quality grass straw (4% CP). Treatments (TRT) included an unsupplemented control (CON) and a ...

BACKGROUND Peripheral neuropathy (PN) is a frequent complication of chronic HIV infection. We prospectively studied individuals with primary HIV infection (<1 year after transmission) to assess the presence of and laboratory associations with PN in this early stage. METHODS Standardized examination and analysis of blood and cerebrospinal fluid (CSF) was performed in participants with laborato...