Abbreviations: HMG-CoA: 3-Hydroxy-3-Methylglutaryl Coenzyme A; JUPITER: The Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin; LDL-C: Low Density Lipoprotein Cholesterol; TG: Triglycerides; HOMAIR: Homeostasis Model Assessment for Insulin Resistance; GIR: Glucose Infusion Rate; FPG: Fasting Plasma Glucose; CK: Creatinine Phosphokinase; AST: Aspart...

conclusions the results suggest that physical activity improves metabolic parameters, which interfere in the development of fatty liver and has a protective role against the development of nafld. results statistical analysis demonstrated that the training group had significant changes in weight, bmi, tc, tg, ldl, vldl, hdl/ldl, tc/ hdl, ast and alt, whereas there was no significant change in hd...

Laggera alata extract (LAE) was quantitatively analyzed, and its principle components isochlorogenic acids were isolated and authenticated. Protective properties of LAE were studied using a d-galactosamine (d-GalN)-induced injury model in neonatal rat hepatocytes and a d-GalN-induced acute liver damage model in mice. Meanwhile, the effect of isochlorogenic acids derived from LAE on d-GalN-induc...

high intensity workout provokes damage in muscles with an effect on muscle physiology and function. today, serum levels of creatine and aspartate aminotransferase are widely used as biochemical markers of muscle damage in order to determine the functional status of muscle tissues in both pathological and physiological conditions. this study investigated the effect of a futsal match on some bioc...

Introduction: Acetaminophen is a widely used analgesic and antipyretic drug. Although it is considered safe at therapeutic doses, at higher doses, might produces a centrilobular hepatic necrosis that can be fatal. In the present study, the effect of fennel seed on hepatotoxicity induced by acetaminophen was investigated. Correspondenc...

background: cadmium has toxicological significance and there is no effective therapy for its poisoning. objective: the effects of silymarin on the parameters indicative of cadmium-induced toxicity were studied in rats. methods: 130 adult male wistar rats were divided into 13 groups each comprising 10 rats. 1 group as control group was not administered neither cadmium nor silymarin. cadmium chlo...

Exposure to hexavalent chromium compounds is associated with the risk of lung cancer, dermatitis, gastrointestinal ulcers, and other tissue damages. The aim of this study was to compare liver isoenzyme and total serum activities of aspartate aminotransferase (AST) as cytotoxic biomarkers of acute and chronic cytotoxicity of Cr(VI). We investigated the extent of cell damage caused by chromium(VI...

BACKGROUND: Cardiac Troponin I (cTnI) is known as a cardiac biomarker in determining the myocardial damage of diseases which affect the heart muscle. OBJECTIVES: This study aims to evaluate the serum cTnI concentration in Markhoz Breed goats suffering selenium (Se) deficiency and its correlation with electrocardiographic parameters, and activity of creatine kinase (CK) and aspartate aminotransf...