conclusions combination therapy with tretinoin plus topical corticosteroids is safe and effective and provides an alternative in the treatment of patients with vitiligo. objectives recent studies suggest that administration of topical tretinoin, with a corticosteroid, diminishes skin atrophy without impacting the steroid’s anti-inflammatory effects. patients and methods a placebo-controlled, pa...

results researchers have reported that mirnas can repress the expression of important cancer-related genes and might be helpful in the diagnosis and treatment of cancer. during the past two decades, numerous studies have shown that mirnas play an essential role in inhibiting hcc via several different pathways. deregulated mirnas may contribute to carcinogenesis, indicating that mirnas can act a...

ôbjective: to compare the effectiveness and safety of the methylphenidate produced in ïran (stimdate®) with its original brand (ritalin®) in children with âttention deficit hyperactivity disorder (âdhd). methods: ïn this double-blinded randomized clinical trial, 30 patients with âdhd who were 6 to 16 years old, were divided into two groups: 15 in stimdate® and 15 in ritalin® group. the two grou...

an experiment was conducted on eight weak and anaemic goats revealed pale conjunctivae, increased heart rate, rough hair coat, dullness and depression. the haematology showed significantly decreased haemoglobin (7.37±0.16 g %), packed cell volume (pcv)(23.37±0.56%),total erythrocyte count (tec)(8.12±0.18 million/cumm), mean corpuscular haemoglobin (mch) (9.10±0.30 pg) and mean corpuscular volum...

background: treating a chronic disease such as hemophilia is to improve the symptoms and quality of life (qol) of the patients. this study aimed to study the quality of life among hemophilic children and compare the quality of life between patients receiving prophylactic or on demand treatments. materials and methods: in this descriptive-comparative study, we enrolled 60 patients from three mai...

background: coronary artery bypass graft (cabg) surgery is very traumatic and makes patients very nervous. since it is a main task of nurses to improve patients' comfort and safety, this study investigated the effect of therapeutic touch in cardiovascular patients' anxiety before cabg surgery. methods: in a controlled clinical trail study the simple random sampling was used to select 44 patient...

the purpose of this paper was to review the commercially available periodontal dressings, their physical and chemical properties, biocompatibility and therapeutic effects. electronic search of scientific papers from 1956 to 2012 was carried out using pubmed, scopus and wiley interscience search engines using the searched terms periodontal dressing, periodontal pack. numerous in vitro and in viv...

objective(s) the role of therapeutic drug monitoring (tdm) in patient care has grown rapidly since its introduction three decades ago. the aim of present study was to evaluate the possible relationship between serum levels and the clinical response of valproic acid (vpa). materials and methods in the present study we evaluated a homogeneous group of adult patients receiving vpa monotherapy. a t...

objective: newbouldia laevis seem, is an ubiquitous perennial plant belonging to the family bignoniaceae with varying applicability in ethnomedicine. methods: the anticonvulsant effect of the aqueous extracts of root and stem bark preparations was undertaken using standard techniques. results: results showed that the ld50 in mice was 489.8mg/kg body weight while 5.6mg/kg body weight protected m...