Steroid hormones have been implicated in the etiology and/or progression of epithelial ovarian cancer. As ovarian surface epithelial cells are growth inhibited by transforming growth factor beta (TGF-beta), we tested whether steroid hormones could regulate the expression of TGF-beta1 or its receptors in ovarian cancer cells, as assessed by quantitative reverse transcription-PCR. Treatment of ov...

Plants use many strategies to defend themselves against animals that eat plants, also called herbivores. One clever way some myrmecophytes, do this is by teaming up with ants. Myrmecophytes are plants have evolved close relationships In return for protection from herbivores, myrmecophytes provide ants food and/or shelter. Sounds like a great deal, right? Yes, but sometimes working can be tricky...

Welcome again to " Hey — it works! " , a column devoted to (L A)T E X and META tips and tricks. This issue is devoted to a single topic, a sequel to an earlier article on creating ornamental rules: we show how to construct ornamental boxes out of individual symbols. Please note that I have moved. My new contact details are given at the end of this article. Unfortunately , mail is not being forw...

The dire prognosis of pancreatic cancer has not markedly improved during past decades. The present study was carried out to explore the effect of Qingyihuaji formula (QYHJ) on inhibiting pancreatic cancer and prolonging survival in related Notch signaling pathway. Proliferation of pancreatic cancer cells (SW1990 and PANC-1) was detected by MTT assay at 24, 48, and 72 h with exposure to various ...

In order to achieve a better outcome for pancreatic cancer patients, reliable biomarkers are required which allow for improved diagnosis. These may emanate from a more detailed molecular understanding of the aggressive nature of this disease. Having previously reported that Notch3 activation appeared to be associated with more aggressive disease, we have now examined components of this pathway ...

JCB • VOLUME 177 • NUMBER 1 • 2007 4 Hey, I’m still replicating! C heckpoints exist to ensure the genome is accurately replicated each cell division. But yeast cells don’t bother to check that replication is actually completed, report Jordi Torres-Rosell, Luis Aragón (MRC Clinical Sciences Centre, London, UK), and colleagues. The team was not initially looking for a replication completion check...

The idea of paying donors in order to make more human bodily material available for therapy, assisted reproduction, and biomedical research is notoriously controversial. However, while national and international donation policies largely oppose financial incentives they do not treat all parts of the body equally: incentives are allowed in connection to the provision of some parts but not others...