Abstract FtsZ is a key component in bacterial cell division, being the primary protein of presumably contractile Z ring. In vivo and vitro, it shows two distinctive features that could so far, however, not be mechanistically linked: self-organization into directionally treadmilling vortices on solid supported membranes, shape deformation flexible liposomes. cells, circumferential was shown to r...

To address the role of transient torsional stress in transcription, we have utilized the regulated expression of HO endonuclease in yeast to create double-strand breaks in DNA templates in vivo at preselected sites. Linearization of circular minichromosomes, either 2 kb upstream or immediately downstream of a lacZ reporter gene controlled by the yeast metallothionein gene (CUP1) promoter, did n...

Accepted: 31.12.2014 In this study, analysed using finite element method (FEM) of biomechanical behaviours of human femur model under the different loads. Geomagic and Soldiworks program were used for 3D model human of femur model, and Ansysworkbench was used for finite element analysis (FEA). Compression, tension, bending and torsional loading were applied to 3D human femur model. Femur bone w...

This paper presents an analytical method to calculate the buckling stress of a rectangular thin plate under nonuniform applied axial stresses. Two cases are considered, buckling of a plate simply supported on all four sides and buckling of a plate simply supported on three sides with one unloaded edge free and the opposite unloaded edge rotationally restrained. These two cases illustrate the in...

It is shown that local denaturation can be a natural consequence of supercoiling, even in environments where base pairing of linear DNA is energetically favored. Any change in the molecular total twist from its unstressed value is partitioned between local denaturation and smooth twisting in both the native and coil regions so as to minimize the total conformational free energy involved. Thresh...

Biological filaments such as DNA or bacterial flagella are typically curved in their natural states. To elucidate the interplay of viscous drag, twisting, and bending in the overdamped dynamics of such filaments, we compute the steady-state torsional stress and shape of a rotating rod with a kink. Drag deforms the rod, ultimately extending or folding it depending on the kink angle. For certain ...