Scientists in all sectors have been raising concerns in recent years about the lack of reproducibility of biomedical research results. An analysis of in-house validation efforts at Bayer HealthCare found that <25% of potential targets could be reproduced in-house.1 Similarly, of 53 “landmark” studies selected because they described completely new findings, only 11% could be confirmed in-house b...

New vocabularies are rapidly evolving in the literature relative to the practice of clinical medicine and translational research. To provide integrated access to new terms, we developed a mobile and desktop online reference-Marshfield Dictionary of Clinical and Translational Science (MD-CTS). It is the first public resource that comprehensively integrates Wiktionary (word definition), BioPortal...

1- Department of Medical History, School Persian Medicine, Tehran University Sciences, Tehran, Iran 2- Translational Ophthalmology Research Center, Farabi Eye Hospital, , [email protected]

Treatment of dominantly inherited muscle disorders remains a difficult task considering the need to eliminate the pathogenic gene product in a body-wide fashion. We show here that it is possible to reverse dominant muscle disease in a mouse model of facioscapulohumeral muscular dystrophy (FSHD). FSHD is a common form of muscular dystrophy associated with a complex cascade of epigenetic events f...

BACKGROUND Medical research strives to improve health; community-engaged research (CEnR) supports translation to the community. METHODS This article describes the use of andragogical theory to develop asynchronous CEnR training. RESULTS A total of 43 researchers and community members completed at least one module. The majority (67%-100%) stated that training met their educational needs and ...