Drug Free Tumor Theranostics In article number 2205165, Tymish Y. Ohulchanskyy and co-authors introduce hemoglobin nanocrystals for drug free, synergistic selective theranostics of colon cancer. After intravenous (i.v.) injection, these target tumor react with tumor-specific H2S H2O to enable magnetic resonance imaging guided photothermal therapy produce •OH chemodynamic therapy.

Melanocortin-1 (MC1) receptor is an attractive melanoma-specific target for the development of α-MSH peptide based imaging and therapeutic agents. In this work a new lactam bridge α-MSH analogue was synthesized and radiolabeled with 99mTc via HYNIC chelator and tricine as co-ligand. Also, stability in human serum, receptor bound internalization and tissue biodistribution in tumor bearing nude m...

Backgrounds: Bleomycin (BLM) has been labeled with radioisotopes and widely used in therapy and diagnosis. In this study BLM was labeled with [62Zn] zinc chloride for oncologic PET studies. Materials and methods: The complex was obtained at the pH=2 in normal saline at 90 ° C in 60 min. Radio-TLC showed an overall radiochemical yield of 95-97% (radiochemical purity > 97%). Stability of complex ...

Melanocortin-1 (MC1) receptor is an attractive melanoma-specific target for the development of α-MSH peptide based imaging and therapeutic agents. In this work a new lactam bridge α-MSH analogue was synthesized and radiolabeled with 99mTc via HYNIC chelator and tricine as co-ligand. Also, stability in human serum, receptor bound internalization and tissue biodistribution in tumor bearing nude m...

Background: Image-guided radiotherapy used multiple imaging during the radiation therapy course to improve the precision and accuracy of health care provider's treatment. Objectives: This study aims to assess the safety, effectiveness and economic aspects of image-guided radiation therapy for decision-making about this technology in Iran. Methods: In this study, the most important med...

calcifying aponeurotic fibroma (caf) is a rare, benign fibroblastic tumor that typically occurs in the palms of the hands and soles of the feet, in children and adolescents. due to its infiltrative nature, this tumor can mimic malignancy on preoperative magnetic resonance imaging (mri) and has a predilection for local recurrence. there are very few reports in the literature that describe featur...

Desmoid tumor is a rare soft tissue and accounts less than 1% of retroperitoneal tumor. It pathologically benign tumor, while clinical behavior aggressive, showing high rate local recurrence. consists spindle cell, collagen myxoid matrix thus it shows diverse imaging patterns according to its composition. In this case report, surgically diagnosed desmoid presented.