A hospital series of 1042 duodenal ulcer patients was examined to determine the relationship of the age of onset of ulcer dyspepsia with the blood group and with the family history of ulcer dyspepsia. It was found that those patients whose symptoms begin in the first two decades of life (early onset patients) contain a significantly larger proportion of group A, B, and AB subjects and a signifi...

Background: Cytotoxin-associated gene A (CagA)-positive strains of Helicobacter pylori are associated with gastroduodenal diseases. Evidences have suggested that the type of H pylori CagA EPIYA motifs may be associated with specific disorders (i.e., gastritis, peptic ulcer, or gastric cancer).  We investigated the prevalence of different EPIYA motifs (A, B, C, or D) in H. pylori strains is...

Introduction: Duodenal Ulcer is one of the most common gastrointestinal disorders encountered in clinical practice. It causes various distressing symptoms like dyspepsia, nausea and vomiting, abdominal bloating weight gain due to post prandial amelioration symptoms. Commonest complications include upper bleeding, increased Blood Urea Nitrogen (BUN) varying degrees anaemia with associated fatigu...

Studies of the epidemiology of dyspepsia have been complicated by the use of different symptom definitions, subject populations and time frames of investigation. Published figures for the prevalence of dyspepsia vary from 20% to 40%, of which perhaps only a quarter can be attributed to peptic ulcer disease. General practitioners see only a fraction of the dyspepsia within the community, the maj...

Abstract Background: The role of psychological factors in peptic ulcer disease (PUD) and functional dyspepsia (FD) has not been clearly determined. In this study the role of conflict management styles, psychiatric symptoms, and alexithymia were assessed in patients with PUD and FD and in the healthy individuals. Methods: Ninety subjects [30PUD (15 women, 15 men), 30 FD (15 women, 15 men), and...

Helicobacter pylori infection of the stomach is associated with gastritis and peptic ulceration and may be causative. A noninvasive test for this organism might be useful in managing some patients with dyspepsia without the need for further investigation. We have evaluated a new commercially available serological test (Helico-G ELISA, Porton Cambridge, UK) for this infection to assess its diagn...

Results: The commonest symptoms were epigastric pain, other upper abdominal pain, and dyspepsia while common signs were epigastric and right upper quadrant tenderness, and epigastric mass. Complete data was obtained in 172 patients of which 114 had abnormal findings. The commonest were duodenal ulcer, gastritis and duodenitis. Less common findings were gastric ulcer, gastric cancer and oesophag...