OBJECTIVES To examine risk factors for the development of squamous cell carcinoma (SCC) and basal cell carcinoma (BCC) in a cohort of heart transplant (HT) recipients and, in particular, to evaluate the role of the cumulative doses of different immunosuppressive drugs. DESIGN Prospective nonconcurrent study. SETTING A dermatology clinic at a university hospital. PATIENTS A total of 230 HT...

Attention bias modification training (ABMT) is a promising treatment for anxiety disorders. Recent evidence suggests that attention training towards positive stimuli, using visual-search based ABMT, has beneficial effects on anxiety and attention biases in children. The present study extends this prior research using distinctive techniques designed to increase participant learning, memory conso...

Purpose The purpose of this paper is to evaluate the impact on stress and work-related outcomes an app-delivered mindfulness-based program (MBP; Headspace®) offered employees in a UK higher education (HE) institution. Design/methodology/approach Using randomized waitlist control trial design, participants were randomly allocated be (MBP) immediately for 2 months or after waiting list period (WL...

Using a recently developed bead-spring model for semiflexible polymers that takes into account their natural extensibility, we report an efficient algorithm to simulate the dynamics for polymers like double-stranded DNA (dsDNA) in the absence of hydrodynamic interactions. The dsDNA is modeled with one bead-spring element per base pair, and the polymer dynamics is described by the Langevin equat...

Abstract Life Cycle Costing (LCC) is a cost estimating approach for project and asset planning delivery that considers the direct indirect costs incurred over entire life cycle of an asset. This can be expanded to concept Whole Cost (WLC), which additionally externalities benefits. WLC demonstrate financial impacts, both positive negative, on its environment, in other words it show complete val...

Non-polypoid (flat and depressed) colorectal neoplasms (NP-CRNs) are more difficult to detect by conventional white light colonoscopy (WLC) or computed tomography colonography, because the subtle findings can be difficult to distinguish from those of normal mucosa. Narrow band imaging (NBI) has been reported to highlight the mucosal capillaries of neoplastic lesions, and thus increase the detec...

We numerically examine the extension of tethered worm-like chains in shear flow, obtaining agreement with scaling arguments that invoke thermal fluctuations and the specific nonlinearity of the WLC force law. The transient tension distribution is obtained and likewise found to reflect nonlinearity and finite extensibility. Cyclic dynamics of the chain free end are observed. Numerical simulation...