نتایج جستجو برای: اس دی 208
تعداد نتایج: 30476 فیلتر نتایج به سال:
Increased synthesis of Apolipoprotein A-I (ApoA-I) and HDL is believed to provide a new approach to treating atherosclerosis through the stimulation of reverse cholesterol transport. RVX-208 increases the production of ApoA-I in hepatocytes in vitro, and in vivo in monkeys and humans, which results in increased HDL-C, but the molecular target was not previously reported. Using binding assays an...
form (18). Address for reprint requests: J. M. Pascual, Department of Neurology, Box 164, Neurological Institute of New York, 710 W. 168th St.,
کرم سیب Cydia pomonella L.، آفت کلیدی باغات سیب میباشد که هر سال چندین بار سموم مختلف علیه این آفت به کار گرفته میشود. به منظور دستیابی به یک حشرهکش جدید و مؤثر روی این آفت و جایگزین کردن آن به جای سموم کم اثر، آزمایشی در قالب طرح بلوک های کامل تصادفی با 6 تیمار در چهار تکرار انجام گرفت. در این آزمایش کارایی سه دز 400،500 و600 پی پی ام حشره کش جدید کالیپسو او- دی به همراه فرمولاسیون ا...
این پژوهش به منظور مقایسه مهارتهای سه گانه مدیران مدارس فرزانگان، نمونه دولتی و عادی منطقه 10 آموزش پرورش تهران انجام شد .روش پژوهش از لحاظ هدف کاربردی و در زمره تحقیقات توصیفی قرار دارد.جامعه آماری پژوهش را معلمان مدارس فرزانگان، نمونه دولتی و عادی آموزش و پرورش منطقه 10 شهر تهران تشکیل می دهند که تعداد آنها در حدود 450 نفر گزارش شدهاند.. جهت تعیین حجم نمونه از جدول استاندارد اچ اس بولا بهره گ...
The cytokine transforming growth factor (TGF)-beta, by virtue of its immunosuppressive and promigratory properties, has become a major target for the experimental treatment of human malignant gliomas. Here we characterize the effects of a novel TGF-beta receptor (TGF-betaR) I kinase inhibitor, SD-208, on the growth and immunogenicity of murine SMA-560 and human LN-308 glioma cells in vitro and ...
The aim of the present study was to characterize the effects of BM 208 (N-[4-(5-chloro-2-methoxybenzamidoethyl)benzenesulfonyl]-N'-cyano- N"- cyclohexylguanidine) and BM 225 (1-[4-(5-chloro-2-methoxybenzamidoethyl)benzene sulfonamido]-1-cyclohexylamino-2-nitroethylene), two newly synthesized isosteres of glibenclamide, on ionic and secretory events in rat pancreatic islet cells. Both compounds ...
Purpose The overall mortality rate among human immunodeficiency virus (HIV)-infected patients has significantly declined in the era of highly active antiretroviral therapy (HAART). However, little is known about the causes of death for HIV-infected patients who are hospitalized in acute care hospitals. Methods A retrospective chart review of hospitalized HIV-infected patients from 2004 to 2008 ...
We have seen two kinds of attacks on meaning, both of which undermine the importance or even the existence of private mental states. Quine was skeptical about meanings, but not meaning. It does not follow from Quine’s work that sentences or utterances, or whatever, lack meaning. But Quine does undermine any precise account of reference. Given the inscrutability of reference which, recall, begin...
Objective(s):Transforming growth factor-β(TGF-β) is involved in colorectal cancer (CRC). The SD-208 acts as an anti-cancer agent in different malignancies via TGF-β signaling. This work aims to show the effect of manipulation of TGF-β signaling on some miRNAs implicated in CRC. Materials and Methods: We investigated the effects of SD-208 on SW-48, a colon adenocarcinoma cell line. The cell li...
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