The role of genetic inheritance in brain development has been well characterized, but little is known about the contributions of natural environmental stimuli, such as the effect of light-dark cycles, to brain development. In this study, we determined the role of light stimuli in neuronal cell migration to elucidate how environmental factors regulate brain development. We show that in early pos...

Trehalose is a non-reducing sugar that plays an important role in plant growth and development. To study the role of trehalose on lipid metabolism and gluconeogenesis, Arabidopsis thaliana wild type (WT) and TreF (a line expressing trehalase) were grown on ½ MS medium with or without 100 mM sucrose and or trehalose in light or continuous darkness. In dark, trehalose leads skotomorphoge...

Supernova observations show that the expansion of the universe has been speeding up. This unexpected acceleration is ascribed to a dark energy that pervades space. Supernova data, combined with other observations, indicate that the universe is about 14 billion years old and is composed of about 30%matter and 70%dark energy. New observational programs can trace the history of cosmic expansion mo...

PURPOSE To employ functional manganese-enhanced MRI (MEMRI) to image layer-specific changes in calcium-dependent activities in the rat retina during light versus dark adaptation. METHODS Functional MEMRI at 20 × 20 × 700 μm was used to study light and dark adaptation in the same animals (N = 10) in which one eye was covered and the fellow eye was not. The activity encoding of the light and da...

This paper presents a dark current suppression technique for a light detector in a variable-temperature system. The light detector architecture comprises a photodiode for sensing the ambient light, a dark current diode for conducting dark current suppression, and a current subtractor that is embedded in the current amplifier with enhanced dark current cancellation. The measured dark current of ...

Dark matter, proposed decades ago as a speculative component of the universe, is now known to be the vital ingredient in the cosmos: six times more abundant than ordinary matter, one-quarter of the total energy density, and the component that has controlled the growth of structure in the universe. Its nature remains a mystery, but assuming that it is composed of weakly interacting subatomic par...

Progress in observational cosmology over the past five years has established that the Universe is dominated dynamically by dark matter and dark energy. Both these new and apparently independent forms of matter-energy have properties that are inconsistent with anything in the existing standard model of particle physics, and it appears that the latter must be extended. We review what is known abo...