The aim of this study was to develop and optimize a segregation-free ethyl cellulose-coated extended release multiparticulate formulation to be compressed into tablets without affecting the drug release. Standard tableting excipients (e.g., microcrystalline cellulose, lactose or sorbitol) were layered onto ethyl cellulose-coated propranolol hydrochloride pellets to form a cushion layer in order...

The results are in. Recent studies conducted by an independent testing laboratory show that when it comes to acoustics, commercial cushion makes carpet even better. To specifiers and end-users, it will come as no surprise that properly specified carpet cushion reduces noise when used in a commercial installation. What will be of interest is the degree of improvement that has been quantified in ...

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Matrix metalloproteinases (MMPs) mediate cell migration and tissue remodeling and are important in cardiac development. We examined the expression patterns of two MMP inhibitors, tissue inhibitor of metalloproteinase (TIMP)-2 and TIMP-3, during critical stages of cardiac development. Both TIMP-2 and TIMP-3 mRNA were expressed in the endocardium prior to and during early cushion cell formation. ...

INTRODUCTION Complete endocardial cushion defect is a congenital heart disease characterized by a variable deficiency of the atrioventricular area in the developing heart. The mortality rate for an unrepaired endocardial cushion defect in pregnancy and the postpartum period is high. CASE PRESENTATION We present a rare case of a pregnant woman with complete endocardial cushion defect. A 20-yea...

Abstract In this study, a three degrees of freedom nonlinear air cushion vehicle (ACV) model is introduced to examine the dynamic behavior heave and pitch responses in addition pressure ACV both time frequency domains. The based on compressible flow Bernoulli’s equation thermodynamics isentropic relations along with Newton second law translation rotation. dynamical investigation was numerical s...

This paper describes the formulation and design principles of operation of a pneumatic proximity-to-tactile sensing device for automated recognition of objects within flexible manufacturing environments. This sensing device utilises a densely packed line array of piezoresistive pressure sensors, providing continuous variable output. The sensing head or plane of the device incorporates a corresp...

BACKGROUND Noninvasive ventilation (NIV) via helmet or total facemask is an option for managing patients with respiratory infections in respiratory failure. However, the risk of nosocomial infection is unknown. METHODS We examined exhaled air dispersion during NIV using a human patient simulator reclined at 45° in a negative pressure room with 12 air changes/h by two different helmets via a v...

To effectively improve the tire grounding behaviors of wheelchair robots, an analytical method is proposed to analyze and optimize the tire grounding safety. Firstly, taking the cushion and tires as the vibration isolation elements with stiffness and damping, the vertical vibration model of the human-wheelchair robot is established. Then, taking the random excitation as the typical input, the f...