In this study, a new hybridized machine learning algorithm for urban flood susceptibility mapping, named MultiB-MLPNN, was developed using multi-boosting technique and MLPNN. The model tested in Amol City, Iran, data-scarce city an ungauged area which is prone to severe inundation events currently lacks prevention infrastructure. Performance of the compared with that standalone MLPNN model, ran...

the findings indicate that among the main factors affecting job stress the psycho-social, physical and environmental factors are prior to the other factors. also amongst the psychosocial factors, lack of career promotion opportunities with 0.222 has the most weight and a lack of accountability of the management about the employees' concerns with 0.036 has the least weight; amongst the phys...

We have used the whole cell configuration of the patch-clamp technique to measure sarcolemmal Ca(2+) transport by the Na(+)/Ca(2+) exchanger (NCX) and its contribution to the activation and relaxation of contraction in trout atrial myocytes. In contrast to mammals, cell shortening continued, increasing at membrane potentials above 0 mV in trout atrial myocytes. Furthermore, 5 microM nifedipine ...

A dichotomy exists between rates of nitrogen fixation directly measured by biological techniques, and rates inferred from the geochemical distributions of excess nitrate within the thermocline of the North Atlantic Ocean. Part of the dichotomy relates to the temporal and spatial uncoupling between the event (i.e., nitrogen fixation by diazotrophs) and signal (i.e., excess nitrate (DINxs) in the...

an urban regeneration project is defined as a series of actions determined to accomplish urban regeneration aims that lead to reduce the problems of an area via improving the socioeconomic, physical and environmental conditions. today, urban regeneration is one of key principles in act of planning and it is beyond the urban renewal, urban redevelopment or urban rehabilitation processes because ...

In order to reduce side effects of survivin-inhibiting anticancer therapies, we determined the expression of the survivin transcripts survivin-wild-type (survivin-wt), survivin-DeltaEx3 (DeltaEx3) and survivin-2B (2B) in cryo-preserved tumor and non-malignant bladder tissues (18 tumor and 22 non-malignant samples, including 17 autologous tissue pairs) by quantitative PCR. Furthermore, we invest...

The polar nucleoside drug ribavirin is front-line treatment for chronic hepatitis C virus infection. The human equilibrative nucleoside transporter (ENT) 1 transports ribavirin into erythrocytes where it is phosphorylated. These phosphorylated metabolites accumulate in the erythrocytes and produce dose-limiting hemolytic anemia. Here, we examined the in vitro and ex vivo transport and metabolis...

Recent results suggest that insulin-like growth factor-I (IGF-I) may be involved in the transition of a hemodynamic load into cardiac hypertrophy and that the expression of IGF-I seems to be coupled to increased wall stress. The present study investigated the role of growth hormone (GH) and IGF-I in myocardial hypertrophy induced by volume overload. An aortocaval fistula (ACF) was created in ma...