Introduction Periodic fever, aphthous stomatitis, pharyngitis and adenitis (PFAPA) syndrome is an autoinflammatory disorder of childhood and little is known about the underlying etiology, pathogenesis or the reason behind the success of tonsillectomy. Numerous immune cell types are present in the tonsillar microenvironment, each of which may contribute to the pattern of symptoms observed in PFA...

Stomatitis is a common complaint which is usually considered to run a benign course, although Ebbs (1938) has suggested that during infancy certain forms of the disease may have serious consequences. An attempt has been made to throw further light on the matter by the study of one-hundred-andfifteen children suffering from stomatitis who attended the Casualty Department of the Children's Hospit...

Background—Recurrent aphthous stomatitis (RAS) is a painful condition of unknown etiology, affecting more than 2.5 billion people worldwide. Vitamin deficiencies have been implicated as a possible cause. Methods—The authors conducted a single-center, randomized, parallel-arm, double-masked, placebo-controlled study to examine the effect of daily multivitamin supplementation on the number and du...

OBJECTIVE To find out the relationship between recurrent aphthous stomatitis (RAS) with deficiencies of haemoglobin, haematocrit, serum vitamin B12, serum Ferritin and red blood cells (RBC) Folate level. STUDY DESIGN An analytical cross-sectional study. PLACE AND DURATION OF STUDY Department of Oral Health Sciences, Shaikh Zayed Federal Postgraduate Medical Complex, Lahore, from February to...

statement of the problem: recurrent aphthous stomatitis (ras) is one of the most common lesions in the oral cavity. due to its multifactorial nature, there is no definitive treatment for ras. laser therapy is one of the suggested treatments to reduce patient’s discomfort. purpose: the purpose of the present clinical trial is to assess the effect of low and high level laser therapy on pain contr...

Celiac disease (CD) diagnosis can be extremely challenging in the case of atypical patterns. In this context, oral signs seem to play a decisive role in arousing suspicion of these forms of the disease. At the same time, the different expressions of the HLA-DQB1∗02 allele apparently seem to facilitate the interpretation of signs and highlighted symptoms. The aim of this work was to verify wheth...

Oral ulcerations are common lesions encountered in private practice. Oral ulcers can have a localised aetiology or be a manifestation of a variety of systemic conditions or disorders (see Table I). Appropriate management depends on the correct diagnosis, which at times can be difficult due to similar clinical features. The aetiology, diagnosis and management of the most common non-viral ulcerat...

This study aimed to evaluate the efficacy and safety of topical treatment with natural herbal medicines on recurrent aphthous stomatitis (RAS). Nine electronic databases were searched to identify the randomized controlled trials and clinical controlled trials that reported the potential effect of natural herbal medicines on RAS published in Chinese or English. Ulcer size and duration, and remis...

BACKGROUND The frequency of recurrent aphthous stomatitis (RAS), the most common oral mucosa lesions seen in primary care, is up to 25% in the general population. However, there has been no optimal therapeutic approach. Our objective was to confirm our previous clinical observation of the beneficial treatment of RAS with vitamin B(12). METHODS A randomized, double-blind, placebo-controlled tr...

BACKGROUND Behçet's disease (BD) is a chronic, relapsing, systemic vasculitis of unknown aetiology. The involvement of oral mucosal surfaces represents the onset feature of the disease in the majority of patients. OBJECTIVE The aim of this study was to evaluate the periodontal status of BD patients and then compare with recurrent aphthous stomatitis (RAS) patients and healthy controls. We als...