Artemisinin and its derivatives are very important new class of antimalarial drugs. One of the most important artemisinin derivatives is artemether. The antiparasitic activity of artemether as a derivative of artemisinin is related to endoperoxide bridge in its structure. The aim of this study was the evaluation of antileishmanial effect of artemether, with more focus on its apoptotic effect. I...

Artemisinin and its derivatives are very important new class of antimalarial drugs. One of the most important artemisinin derivatives is artemether. The antiparasitic activity of artemether as a derivative of artemisinin is related to endoperoxide bridge in its structure. The aim of this study was the evaluation of antileishmanial effect of artemether, with more focus on its apoptotic effect. I...

Background: Selection of human spermatozoa prior to assisted reproduction is currently based on motility and morphology. Recently, Zeta method has been introduced for normal sperm selection based on sperm surface charges. In addition, one of the features of apoptosis is the externalization of phosphatidylserine (PS), which are normally present on the inner leaflet of the sperm plasma membrane. ...

background: more than 40% of infertilities are due to endometriosis. ultrustructural and histochemical study of endometrium will help to clarify the etiology of endometriosis. objective: the aim of the present study was to investigate the ultrastructure and occurrence of apoptosis in endometrial cells of women with or without endometriosis. materials and methods: in the present case-control stu...

Abstract Current antiepileptic strategies aim to normalize the interaction of excitatory and inhibitory systems, which is ineffective in treating patients with drug-resistant epilepsy. Neuroinflammatory processes epileptic focus its perifocal area can trigger apoptosis also contribute development drug resistance. The level pro- anti-apoptotic proteins (p-NF-kB, TNF-α, p53, FAS, caspase-3, caspa...

objective: this study is an attempt to examine the anti apoptotic effects of bio on rat msc culture. materials and methods: rat marrow primary cell culture was established and exposure groups were defined; cultures with 0.01, 0.1, 1 μm bio. cells cultured without bio treatment were used as controls. during culture expantion, the average doubling time, as an index of the rate of cell growth, wer...