Zuhair Hassan
Department of Immunology, Medical School, Tarbiat Moddares University, Tehran, Iran
[ 1 ] - Ginger extract modulates the expression of IL-12 and TGF-β in the central nervous system and serum of mice with experimental autoimmune encephalomyelitis
Objective: The main function of IL-12 is differentiation of naive T cells intoTh1 cells and TGF-β is a powerful immunoregulatory cytokine. The immunomodulatory and anti-inflammatory properties of ginger have also been reported in some studies. The aim of this study was to evaluate the effects of ginger extract on the expression of IL-12 and TGF-β in a model of experimental autoimmune encephalom...
[ 2 ] - In-vitro evaluation of antileishmanial activity and toxicity of artemether with focus on its apoptotic effect
Artemisinin and its derivatives are very important new class of antimalarial drugs. One of the most important artemisinin derivatives is artemether. The antiparasitic activity of artemether as a derivative of artemisinin is related to endoperoxide bridge in its structure. The aim of this study was the evaluation of antileishmanial effect of artemether, with more focus on its apoptotic effect. I...
[ 3 ] - In-vitro evaluation of antileishmanial activity and toxicity of artemether with focus on its apoptotic effect
Artemisinin and its derivatives are very important new class of antimalarial drugs. One of the most important artemisinin derivatives is artemether. The antiparasitic activity of artemether as a derivative of artemisinin is related to endoperoxide bridge in its structure. The aim of this study was the evaluation of antileishmanial effect of artemether, with more focus on its apoptotic effect. I...
[ 4 ] - An HIV-1 Mini Vaccine Induced Long-lived Cellular and Humoral Immune Responses
Memory formation is the most important aspect of a vaccine which can guarantee long-lasting immunity and protection. The main aim of the present study was to evaluate the memory immune responses after immunization with a mini vaccine. Mice were immunized with human immunodeficiency virus-1 P24-Nef fusion peptide and then cellular and humoral immune responses were evaluated. In order to determin...
[ 5 ] - اثر ضدقارچی عصاره آبی سیر تازه، سیر کهنه و ترشی سیر بر رشد کاندیدا آلبیکنس در شرایط آزمایشگاهی
اهداف: در دهه‌های اخیر فعالیت ضدقارچی سیر مشخص شده است. سیر سبب مهار رشد کاندیدا آلبیکنس می‌شود. سیر به شکل‌های مختلف به‌منظور پیشگیری یا درمان طیفی از عفونت‌ها، از جمله عفونت‌های کاندیدیایی، مورد استفاده قرار می‌گیرد. در مطالعه حاضر، اثر ضدقارچی عصاره آبی سیر تازه، کهنه و ترشی بر سوش استاندارد کاندیدا آلبیکنس مورد مقایسه قرار گرفت. روش‌ها: در این مطالعه تجربی، عصاره آبی سیر با استفاده از روش م...
[ 6 ] - Enhancement effect of Shark Cartilage extract on treatment of Leishmania infantum with Artemisinin and Glucantime and evaluation of killing factors and apoptosis in vitro condition
In this study we examined enhancement effects of Artemisinin plus Glucantime and shark cartilage extract, on promastigotes and amastigotes of L.infantum in in vitro condition.The toxicity of artemisinin, glucantime and shark cartilage extract on the L. infantum promastigotes and amastigote-infected macrophages was evaluated using MTT assay. The role of these drugs in inducing apoptosis in proma...
[ 7 ] - Enhancement effect of Shark Cartilage extract on treatment of Leishmania infantum with Artemisinin and Glucantime and evaluation of killing factors and apoptosis in vitro condition
In this study we examined enhancement effects of Artemisinin plus Glucantime and shark cartilage extract, on promastigotes and amastigotes of L.infantum in in vitro condition.The toxicity of artemisinin, glucantime and shark cartilage extract on the L. infantum promastigotes and amastigote-infected macrophages was evaluated using MTT assay. The role of these drugs in inducing apoptosis in proma...
نویسندگان همکار