Zahra Taghipour

Department of Histology, Medical School, Rafsanjan University of Medical Sciences, Rafsanjan, Iran

[ 1 ] - Ginger extract modulates the expression of IL-12 and TGF-β in the central nervous system and serum of mice with experimental autoimmune encephalomyelitis

Objective: The main function of IL-12 is differentiation of naive T cells intoTh1 cells and TGF-β is a powerful immunoregulatory cytokine. The immunomodulatory and anti-inflammatory properties of ginger have also been reported in some studies. The aim of this study was to evaluate the effects of ginger extract on the expression of IL-12 and TGF-β in a model of experimental autoimmune encephalom...

[ 2 ] - Effect of maternal fluoxetine exposure on lung, heart and kidney development in rat neonates

Objective(s): Depression during pregnancy negatively affects fetal development. Fluoxetine as a selective serotonin reuptake inhibitor (SSRIs) is used for treatment of gestational depression. This study is trying to determine the effects of fluoxetine on the renal, heart and lung development.Materials and Methods: Fifteen pregnant rats were treated with fluoxetine at 7 mg/kg from days 0 to 21 o...

[ 3 ] - The Modulatory Effects of Vitamin D on the Expression of IL-12 and TGF-β in the Spinal Cord and Serum of Mice with Experimental Autoimmune Encephalomyelitis

Background & objective The immunoregulatory effects of transforming growth factor (TGF)-βand interleukin-12 (IL-12) and immunomodulatory actions of vitamin D (VD) were reported in several studies. This study aims to evaluate VD effects on IL-12 and TGF-β expression in experimental autoimmune encephalomyelitis (EAE). Methods:</str...

[ 4 ] - Ceftriaxone improves senile neurocognition damages induced by D-galactose in mice

Objective(s): Ceftriaxone (Cef), a beta-lactam antibiotic, is accompanied by antioxidant and anti-inflammatory properties. It has been shown that Cef has beneficial effects on Alzheimer’s disease. In the current investigation, the effect of Cef in a mice model of aging was investigated. Materials and Methods: Forty male mice were equally...

[ 5 ] - Effect of Metformin on Some Cognitive Functions in Old Rats

Introduction: Aging is a complex process and is considered as a risk factor for many diseases such as hypertension, Alzheimer, cancer, depression and anxiety. Recently, it has been shown that metformin, an anti-diabetic drug, has important neurological effects such as preventing memory loss, stroke, anxiety, inflammation and seizures. Therefore, the aim of this study was investigating the effec...

[ 6 ] - Musculoskeletal Status and Quality of Life among Faculty Members of Rafsanjan University of Medical Sciences, Iran, 2019

Background: Musculoskeletal diseases are often studied in people with hard occupations, such as in factory workers, but they are less often studied in people with intellectual occupations. Accordingly, this study aims to examine musculoskeletal diseases and their relationship with quality of life among faculty members of Rafsanjan University of Medical Sciences (RUMS) to design corrective exerc...

[ 7 ] - A Survey on Morphometry and Topography of Nutrient Foramina and Measurement of Other Anthropometric Parameters in Human Femora and Tibiae: A Descriptive Study

Background and Objectives: Measuring the dimensions of bones is essential from the perspective of surgery related to bones and joints. The position of the nutrient foramen and the bones' dimensions vary in different populations. The aim of this study was to determine some anthropometric dimensions and topography of nutrient foramina in the femora and tibiae. Materials and Methods: In this desc...

[ 8 ] - Comparing the BMI and Some Physical Parameters Before and One Year After the COVID-19 Pandemic among High School Students in Rafsanjan City, Iran

Background: Obesity has many side effects and deadly risks. During the COVID-19 pandemic, school closures have been affecting the lifestyle of students worldwide. This study aims to assess changes in the BMI and some physical parameters among students before and one year after the COVID-19 pandemic in Rafsanjan City, Iran. Materials and Methods: In this descriptive study, the sample included 7...