Gholamreza Bazmandegan
Physiology-Pharmacology Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran|Department of Physiology and Pharmacology, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
[ 1 ] - TRPV1 receptor-mediated expression of Toll-like receptors 2 and 4 following permanent middle cerebral artery occlusion in rats
Objective(s): Stroke is known as a main cause of mortality and prolonged disability in adults. Both transient receptor potential V1 (TRPV1) channels and toll-like receptors (TLRs) are involved in mediating the inflammatory responses. In the present study, the effects of TRPV1 receptor activation and blockade on stroke outcome and gene expression of TLR2 and TLR4 were assessed following permanen...
[ 2 ] - Association of HbA1c Levels with Extent and Functional Status of Ischemic and Hemorrhagic Stroke
Background:HbA1c is an established diagnostic index which is used to assess diabetes mellitus. The aim of this study was to evaluate the association between HbA1c level with the types of stroke as well as the extent and functional status of ischemic stroke (IS) and hemorrhagic stroke (HS) in patients. Methods: In this cross-sectional study, we evaluated 120 pa...
[ 3 ] - Sumatriptan ameliorates renal injury induced by cisplatin in mice
Objective(s): Cisplatin (Cis) is an anticancer compound, which is used for the treatment of various cancers. Sumatriptan (Suma) is a selective agonist of 5-hydroxytryptamine 1B/1D (5HT1B/1D) receptor, which is prescribed for the management of migraine. It is well-established that Suma has anti-inflammatory and antioxidant properties. We have explored the protective effe...
[ 4 ] - The Cut-off Point of Ferritin, Procalcitonin, and Serum CRP Levels in the Peripheral Blood of Neonates Suffering from Sepsis
Background: Sepsis is regarded as a critical clinical status in neonates. Since blood culture is a time-consuming method, the present study was conducted to investigate the serum level of Ferritin, Procalcitonin, and CRP in the peripheral blood of term neonates suspected with sepsis to have a quicker diagnosis for the disease. Methods: In the pres...
[ 5 ] - Ceftriaxone improves senile neurocognition damages induced by D-galactose in mice
Objective(s): Ceftriaxone (Cef), a beta-lactam antibiotic, is accompanied by antioxidant and anti-inflammatory properties. It has been shown that Cef has beneficial effects on Alzheimer’s disease. In the current investigation, the effect of Cef in a mice model of aging was investigated. Materials and Methods: Forty male mice were equally...
[ 6 ] - The Effect of Intravenous Fluid Therapy before Spinal Block on Postdural Headache in Women Undergoing Elective Cesarean Section: A Clinical Trial
Background and Objectives: Postdural puncture headache is a complication of spinal block in postpartum period, which increases the cost of hospitalization and limits maternal activity. The purpose of this study was to evaluate the role of intravenous fluid therapy before the onset of spinal block in the incidence, severity and duration of postdural puncture headache. Materials and Methods: The...
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