«ascorbic acid»
۱۵٬۸۰۳ نتیجهRelationship of ascorbic acid to blood lead levels.
CONTEXT Some animal studies suggest that orally administered ascorbic acid may chelate lead and decrease the risk of the toxic effects of lead. However, results from several small studies in humans have yielded inconclusive evidence of a beneficial effect of ascorbic acid on lead
Reassessment of changes in leucocyte and serum ascorbic acid after acute myocardial infarction.
After an acute myocardial infarction, there is an apparent acute fall in leucocyte ascorbic acid associated with an acute rise in white blood cells and serum cortisol. The apparent fall in leucocyte ascorbic acid is the result of the granulocytosis which occurs after the infarcti
Effects of ascorbic acid on sperm motility, viability, acrosome reaction and DNA integrity in teratozoospermic samples
BACKGROUND Oxidative stress in teratozoospermic semen samples caused poor assisted reproductive techniques (ART) outcomes. Among antioxidants, ascorbic acid is a naturally occurring free radical scavenger and as such its presence assists various other mechanisms in decreasing num
The effects of ascorbic acid on collagen synthesis by cultured human skin fibroblasts.
Human skin fibroblasts in in vitro culture secrete over fifty proteins into the culture medium [l]. Exported proteins include the glycoproteins, fibronectin, laminin and the collagens, all of which are involved in the composition of the extracellular cell matrix. Information is l
The Mechanism of Ascorbic Acid - Induced Differentiation of ATDC 5 Chondrogenic Cells 1
25 The ATDC5 cell line exhibits a multistep process of chondrogenic differentiation analogous to 26 that observed during endochondral bone formation. Previous investigators have induced 27 ATDC5 cells to differentiate by exposing them to insulin at high concentrations. We have 28
The mechanism of ascorbic acid-induced differentiation of ATDC5 chondrogenic cells.
The ATDC5 cell line exhibits a multistep process of chondrogenic differentiation analogous to that observed during endochondral bone formation. Previous investigators have induced ATDC5 cells to differentiate by exposing them to insulin at high concentrations. We have observed sp
The chemical identification of ascorbic acid in urine.
DURING the past 3 years several methods have been proposed, and widely used, for the estimation of ascorbic acid in urine. They all depend on the reducing properties of ascorbic acid and are all non-specific. By careful limitation of conditions it is possible, with these methods,
Ascorbic acid deficiency elevates serum level of LDL-cholesterol in a rat mutant unable to synthesize ascorbic acid.
The effect of ascorbic acid deficiency on serum levels of high density lipoprotein- (HDL-), low density lipoprotein- (LDL-), very low density lipoprotein- (VLDL-) and chylomicron-cholesterol was examined in ODS-od/od rat (ODS rat), that is a rat mutant unable to synthesize ascorb
Ascorbic acid enhances endothelial nitric-oxide synthase activity by increasing intracellular tetrahydrobiopterin.
Ascorbic acid enhances NO bioactivity in patients with vascular disease through unclear mechanism(s). We investigated the role of intracellular ascorbic acid in endothelium-derived NO bioactivity. Incubation of porcine aortic endothelial cells (PAECs) with ascorbic acid produced
The human sodium-dependent ascorbic acid transporters SLC23A1 and SLC23A2 do not mediate ascorbic acid release in the proximal renal epithelial cell
Sodium-dependent ascorbic acid membrane transporters SLC23A1 and SLC23A2 mediate ascorbic acid (vitamin C) transport into cells. However, it is unknown how ascorbic acid undergoes cellular release, or efflux. We hypothesized that SLC23A1 and SLC23A2 could serve a dual role, media