The study of dislocation nucleation in close-packed metals by nanoindentation has recently attracted much interest. Here, we address the peculiarities of the incipient plasticity in body centered cubic bcc metals using low index Ta single crystals as a model system. The combination of nanoindentation with high-resolution atomic force microscopy provides us with experimental atomic-scale informa...

BCC: basal cell carcinoma HH: hedgehog IHC: immunohistochemistry mBCC: metastatic basal cell carcinoma SUFU: suppressor of fused INTRODUCTION Basal cell carcinoma (BCC) represents nearly 80% of nonmelanoma primary skin malignancies in the United States. However, metastatic BCC (mBCC) is exceedingly rare, difficult to treat, and associated with high mortality, yet it’s easily preventable. We rep...

INTRODUCTION Organisms of the Burkholderia cepacia complex (BCC) are important pathogens in cystic fibrosis (CF). The majority of those who acquire BCC develop chronic infection but it can also result in rapid decline in a significant minority. In addition, chronic infection with Burkholderia cenocepacia in particular is regarded as a contraindication to lung transplantation in many units. Whil...

Abstract BCC-ESM1 is the first version of Beijing Climate Center’s Earth System Model, and participating in phase 6 Coupled Model Intercomparison Project (CMIP6). The Aerosol Chemistry (AerChemMIP) only CMIP6-endorsed MIP which involved. All AerChemMIP experiments priority 1 seven priorities 2 3 have been conducted. DECK (Diagnostic, Evaluation Characterization Klima) CMIP historical simulation...

Basal cell carcinoma (BCC) presents with diverse clinical features, and several morphologic and histologic variants of BCC have been reported [Sexton et al.: J Am Acad Dermatol 1990;23:1118-1126]. Linear BCC was first described as a new clinical subtype in 1985 by Lewis [Int J Dematol 1985;24:124-125]. Here, we present a case of linear BCC that we recently encountered in an elderly Japanese pat...

We report results of total energy and electronic structure calculations of fcc and bcc silver bulk and surfaces. We find that under normal conditions (positive pressure) bcc silver is not stable. However, if silver is grown with a volume per atom & 10% larger than that of the well-known fcc silver, the total energy of the bcc structure becomes below that of fcc silver. For bcc (110) a surface s...

The purpose of this study was to determine the role of colonial morphology of Burkholderia cepacia complex (BCC) organisms in pathogenicity in a mouse model of pulmonary infection. BCC strain C1394 was rapidly cleared by leukopenic mice after intranasal challenge, whereas a spontaneous variant (C1394mp2) that was indistinguishable from the parent strain by genetic typing persisted in the lungs ...

INTRODUCTION The epidemiology of Burkholderia cepacia complex (Bcc) in cystic fibrosis (CF) is not widely known. METHODS All CF patients with Bcc between 2002 and 2011 were reviewed, and a molecular analysis of isolates was performed. RESULTS The prevalence of Bcc infection was 7.2% (18/250). Molecular analysis of 16 Bcc isolates showed 5 species (7 B. contaminans, 6 B. cepacia, 1 B. cenoce...