BACKGROUND It has been elucidated that Berberis vulgaris (barberry) can alleviate morphine withdrawal syndrome. Also it has been reported that aqueous extract of barberry possibly have inhibitory effect on NMDA receptors. OBJECTIVES In this study, we decided to evaluate the effects of aqueous extract of B. vulgaris fruit on morphine tendency in mice using conditioned place preference (CPP) me...

Seedless barberry (Berberis vulgaris L. var. asperma) is one of the few crops that is only cultivated in eastern parts of Iran. As a new crop there has not been any study to identify phylogenetic relationships of this plant with other related species existing in Iran. In this study, Amplification fragment length polymorphism (AFLP) markers based on four selected primer combinations (EcoRI/Tru1I...

Geomorphologically inaccessible mighty mountain ranges of Karakoram, Hindukush, Himalaya and Pamir have been mother sanctuaries for several ecologically attuned civilizations. Modern changes underway across ethnoecological and ethnobotanical settings among these mountain traditional communities have drastically depreciated folk wisdom and ecological equilibrium. Ethnoclimatic agencies have thre...

Fruits of Berberis asiatica and Pyracantha crenulata are traditionally consumed by local people of north western Himalayan states of India for the treatment of oxidative stress induced ailments. Methanolic extract from mature fruits were evaluated for their total phenolics, related antioxidant compounds and activities. Result showed that Berberis asiatica possesses the higher level of total pol...

The present study was aimed to evaluate the phytochemical, antidiabetic, and cytoprotective properties of Berberis aristata DC. (Berberidaceae) root extracts. After phytochemical evaluation of various extracts of B. aristata roots, the ethanol extract was found to be rich in phytochemicals with the presence of alkaloid determined by the thin layer chromatography; hence ethanol extract was selec...

Background and Aim: In recent years, due to the indiscriminate and irrational use of synthetic drugs, the resistance of pathogenic microorganisms has increased; therefore, new compounds are vitally needed. The purpose of this study was to investigate the effect of ethanolic and aqueous extracts of Berberis vulgaris on Escherichia coli, Klebsiella pneumoniae, Proteu...

Metabolic syndrome (MetS), characterized by a cluster of metabolic abnormalities including hypertension, obesity, type 2 diabetes mellitus (T2DM) and dyslipidemia, is a well-known cardiovascular risk factor (CVRF). Cardiovascular disease (CVD) represents a massive healthcare burden worldwide. In recent years, with regard to the adverse effects of synthetic drugs, increasing attention has been p...

Objective: Berberis vulgaris has antioxidant, hepato--renal protective, antibacterial, lipid lowering, anti-inflammatory and antinociceptive activities. The genus Berberis, has another member called Berberisintegerrima which has not been studied for antinociceptive activity and therefore, this study was aimed to examine the antinociceptive effect oftotal extract and alkaloid fractions of Berber...