INTRODUCTION Accidental hypothermia is a condition associated with significant morbidity and mortality. Hypothermia has been reported to affect left ventricular systolic and diastolic function. However, most of the data come from animal experimental studies. AIM OF THE STUDY The purpose of the present study was to assess the impact of severe accidental hypothermia on systolic and diastolic ve...

The scavenger receptor class B type I (SR-BI) and its human homologue CLA-1 (CD36 and LIMPII Analogous-1) have recently been identified to bind HDL and mediate the selective uptake of HDL lipids. Tissue distribution of both murine and human receptors is quite similar, in that they are expressed abundantly in liver and steroidogenic tissues. However, expression and function of the human SR-BI (h...

We propose a natural cost function for the bi-clustering task, the monochromatic cost. This cost function is suitable for detecting meaningful homogeneous bi-clusters based on categorical valued input matrices. Such tasks arise in many applications, such as the analysis of social networks and in systemsbiology where researchers try to infer functional grouping of biological agents based on thei...

Williams syndrome (WS) is associated with a distinct profile of relatively proficient skills within the verbal domain compared to the severe impairment of visuo-spatial processing. Abnormalities in executive functions and deficits in planning ability and spatial working memory have been described. However, to date little is known about the influence of executive function deficits on navigationa...

In this paper, a bi-objective mixed-integer linear optimization model for Closed-loop Supply Chain Network Design Problem (CLSCND) is developed. The proposed model includes both the forward and reverse directions and includes different types of facilities, namely, manufacturing/remanufacturing centers, warehouses, and disassembly centers. The first objective function tried to minimize the total...

In this research, we propose a bi-objective model for the economic-statistical design of the X-bar and S control charts. The model minimizes out-of-control average time to signal as well as minimizing mean hourly loss-cost where it incorporates the Taguchi loss function. Statistical constraint is considered in the model to achieve desired in-control time to signal. A non-dominated sort...

in this paper, the staff assignment problem considering cross-training of caregivers in health care systems is addressed to determine which staff should be cross-trained for each service and how they should be assigned to services. a bi-objective non-linear mathematical programming model is presented where the first objective function aims to minimize workload balancing, cross-training as well ...

ÐThe grain boundary segregation of Bi in dilute polycrystalline Cu±Bi alloys was systematically studied as a function of temperature and composition. The temperature dependencies of the Gibbsian excess of Bi at the grain boundaries exhibited discontinuous changes at the temperatures close to, but di€erent from the bulk solidus temperatures. The observed segregational phase transition was interp...