Objective(s): Iran is considered as one of the high-prevalence areas for β-thalassemia with a rate of about 10% carrier frequency. Molecular diagnosis of the disease is performed both by direct sequencing and indirectly by the use of polymorphic markers present in the beta globin gene cluster. However, to date there is no reliable information on the application of the markers in the Iranian pop...

 DNA markers are integrally connected to the success of molecular breeding and are fundamentally required by breeders to be able to, a. identify new gene sources in the available biodiversity, b. select parents in order to increase heterosis, c. decrease the number of backcross generations for gene introgression breeding programs, and d. carry out marker-assisted selection (MAS). The present re...

An F(1) mapping population of the septoria tritici blotch pathogen of wheat, Mycosphaerella graminicola, was generated by crossing the two Dutch field isolates IPO323 and IPO94269. AFLP and RAPD marker data sets were combined to produce a high-density genetic linkage map. The final map contained 223 AFLP and 57 RAPD markers, plus the biological traits mating type and avirulence, in 23 linkage g...

Breast cancer (BC) has varied morphological and biological features and is classified based on molecular and morphological examinations. Molecular classification of BC is based on biological gene-expression profiling. In this study, biomarker modulation was assessed during BC treatment in 30 previously untreated patients. Heterogeneity among patients was pathologically diagnosed and classified ...

Houttuynia cordata Thunb., called Yuxingcao in Chinese, is an important medicinal plant and vegetable consumed the southern regions of China. This review aims to summarize studies on phyto-physiological chemistry, cytology, molecular biology, genomics H. cordata. Studies physiology biochemistry have grown over past few decades. Phenotypic agronomic traits, tissue culture, elemental analysis, ph...

Abstract Molecular techniques are powerful tools that can address many research problems in insect ecology. Mitochondrial DNA (mtDNA) is a widely used molecular marker. It easy to use and has favorable biological properties, such as near-neutrality, lack of recombination, clock-like evolutionary rate. However, there some issues involved when using mtDNA data population genetics, species delimit...