نتایج جستجو برای: biological response modifiers
تعداد نتایج: 1383692 فیلتر نتایج به سال:
Recent studies suggest an immune modulator role for Creactive protein (CRP). We have tested the effect of CRP in a tumor system designed for study of métastases.Fibrosarcoma T241 was implanted on one hind foot of syngeneic C57BL/6 mice. After 17 days, the tumor-bearing feet were amputated, and i.v. therapy of liposomes containing CRP or control re agents was started. Examination of the lungs o...
In animal production, alternative strategies to in-feed growth-promoting antibiotics are being developed to increase the resistance of piglets to disease, especially during the weaning transition where they are highly sensitive to digestive disorders. The incorporation in feed of substances able to modulate immune functions, and thus to stimulate host defence, is a strategy which has gained inc...
Increasing evidence demonstrates that radiation acts as an immune stimulus, recruiting immune mediators that enable anti-tumor responses within and outside the radiation field. There has been a rapid expansion in the number of clinical trials harnessing radiation to enhance antitumor immunity. If positive, results of these trials will lead to a paradigm shift in the use of radiotherapy. In this...
We found that PSK has an antiviral effect on human immunodeficiency virus (HIV) in vitro. One of the mechanisms of this effect is attributable to the inhibition of binding of HIV with lymphocytes. Here, we found that PSK inhibits reverse transcriptase in a non-competitive way in vitro. Such inhibition may be important in its anti-HIV effect as well as its inhibitory effect on the binding of HIV...
BACKGROUND IMAgINE 1 assessed 52-week efficacy and safety of adalimumab in children with moderate to severe Crohn's disease. Long-term efficacy and safety of adalimumab for patients who entered the IMAgINE 2 extension are reported. METHODS Patients who completed IMAgINE 1 could enroll in IMAgINE 2. Endpoints assessed from weeks 0 to 240 of IMAgINE 2 were Pediatric Crohn's Disease Activity Ind...
Transformation and change for a better health and care delivery system have been the driving forces behind UK's government initiatives and investments during the past decade. Questions have been raised in terms of how successful these investments have been and to what extent they have delivered their strategic step changes and benefits to the community and to the healthcare system in itself as ...
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