Due to their unique biodegradability, magnesium alloys have been recognized as suitable metallic implant materials for degradable bone implants and bioresorbable cardiovascular stents. However, the extremely high degradation rate of magnesium alloys in physiological environment has restricted its practical application. This paper reports the use of a novel microwave assisted coating technology ...

Silver doped hydroxyapatite was prepared by the precipitation method, using the precursor of hydroxyapatite, CaCl2-0.5M and (NH4) 2HPO4-0.3M; silver sulfate (Ag2SO4) is added to the precursors in order to bring the ions of silver (Ag at 10%) in the structure of hydroxyapatite. The morphology, structure and composition of prepared samples were characterized by X-ray diffraction, the complex ther...

OBJECTIVE To evaluate the compatibility of novel nano-calcium-deficient hydroxyapatite/poly-amino acid (n-CDHA/PAA) complex biomaterials with muscle and bone tissue in an in vivo model. METHODS Thirty-two New Zealand white rabbits were used in this study. Biomaterials were surgically implanted into each rabbit in the back erector spinae and in tibia with induced defect. Polyethylene was impla...

The purpose of this study is to synthesize nano-grained Calcium Hydroxyapatite (HAp) through slip casting technique. For this, hydroxyapatite powders were synthesized using two methods, wet chemical method and Ammoniacal method. The as-prepared powders and calcined powders were characterized using XRD, FTIR, to study the phases of the powders. The hydroxyapatite powder calcined at 1000°C for 2h...

in this investigation, fluor-hydroxyapatite (fha) film was deposited on a titanium substrate by sol-gel method. triethyl phosphite, ammonium fluoride and calcium nitrate in ethanol solutions were used respectively as p, f and ca precursors. typical apatite structures were obtained for all coatings after dipping and subsequent heat treatment at 550, 700 and 800 ºc, the coating layers were invest...

BACKGROUND AND METHODS A nano calcium-deficient hydroxyapatite (n-CDHA)-multi(amino acid) copolymer (MAC) composite bone substitute biomaterial was prepared using an in situ polymerization method. The composition, structure, and compressive strength of the composite was characterized, and the in vitro degradability in phosphate-buffered solution and preliminary cell responses to the composite w...

We presented a case in which massive hydroxyapatite accumulation was observed around the artificial hip joint. A 66-year-old female showed a massive accumulation of fluid in and around the hip joint, and milk-like aspirate was obtained. Her aspirate culture was negative, and sediment analysis by X-ray diffraction showed that its component was hydroxyapatite. Since pain was mild, the patient was...

Porous three-dimensional hydroxyapatite scaffolds were synthesised from aragonitic cuttlefish bones via a microwave based technique. Due to its close similarity to the mineral phase found in the natural human bone matrix, synthetically produced hydroxyapatite is considered a viable apatite substitute for natural bone in a number of biomedical applications. The X-ray diffract ion data confirms t...

Introduction: There have been some reports that various types of hydroxyapatite, other calcium phosphate-based biomaterials, and porous titanium processed with alkali-heat treatment, had osteoinductivity in the muscles of dogs, sheep, pigs, and primates. The mechanism of material-induced osteoinduction has not been well understood. In particular, little has not been known about the reason why o...

The deposition of amorphous calcium salts within the soft tissues is variously called mineralization or calcification. Two forms of calcium salts may be found in the soft tissues: calcium pyrophosphate dihydrate and calcium hydroxyapatite. If bony trabeculae are discernible within the mineralized focus the term ossification is used, sometimes prefixed with the terms ectopic or heterotopic. Ther...