The receptor and the receptor axis CXCL12 / CXCR4 are the two pairs studied in the metastasis of breast cancer. The purpose of this study was to investigate the relationship between the occurrence of CXCR4 / CXCL12 genes polymorphism and the clinical and pathological characteristics of patients with metastatic breast cancer under chemotherapy. Material and methods: Genomic DNA was extracted f...

background : this study retrospectively evaluated the prognostic factors and treatment outcome of patients with hormone-refractory prostate cancer who received chemotherapy. methods :we reviewed records of hormone-refractory prostate cancer patients who received chemotherapy between december 2004 and may 2011 at the clinical oncology and nuclear medicine department, mansoura university and the ...

background: contralateral axillary metastasis (cam) is a rare entity in patients with breast cancer which can occur during the primary breast cancer or its follow-up. different treatment modalities include surgery, radiotherapy, and chemotherapy, but there is no agreement on them. in our review, we found 12 series with available data, 82 patients with synchronous or metachronous contralateral a...

Background: Chemotherapy is an alternative anticancer therapy. In general, side effects that will occur are hair loss, decreased appetite, weight headache, fatigue, mouth ulcer, diarrhea, nausea and vomiting, constipation, nosebleed, skin rash, painful urination, muscle pain, heartburn.Objective: To identify the most least chemotherapy in patients with prostate cancer, bladder testicular cancer...

This study aims to identify various complementary therapies that can overcome nausea and vomiting in breast cancer patients receiving chemotherapy. The method used is a literature search from different online databases. results showed several treat chemotherapy, such as acupressure, yoga, acupuncture, foot massage therapy, breathing exercises guided imagery combined with progressive muscle rela...

Objectives Aggressive cancer therapy places patients at a greater risk for oral complications. Cancer patients suffer from oral toxic effects secondary to antineoplastic therapy (radiotherapy and chemotherapy). The aim of this review is management of the head and neck   cancer patients that specifically emphasizes the prevention and treatment of oral and   dental complications associated with c...

Cancer is the second leading cause of death in the United States and has become a health problem worldwide. The reported incidence of new cancer cases is estimated at 19.3 million, with a mortality rate of 10 million in the world in 2020. There are several therapeutic approaches for cancer, including chemotherapy. Chemotherapy is consuming anti-neoplastic drugs, alone or in combination. However...

Background and objective:Breast cancer is the most common malignancy among women. The Neoadjuvant chemotherapy is the treatment of choice for non-operable tumors. The Ki67 is a proliferation marker that can be used to predict the therapeutic response to chemotherapy and the patients' prognosis. Methods: This retrospective study was carri...