Harnessing Novel Quantitative Pharmacology Approaches to Optimize the Treatment of Children With Tuberculosis James A. Seddon and Mamodikoe K. Makhene Centre for International Child Health, Department of Paediatrics, Imperial College London, United Kingdom; and Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health,...

Departments of Medicine and Pediatrics, University of Chicago, Chicago, USA, 60559, *Department of Physiology, and Section of Respiratory Diseases (Asthma/COPD Research Centre), University of Manitoba, Winnipeg, MB, Canada, R3E 0W3, ‡Biology of Breathing Group, Manitoba Institute of Child Health, Winnipeg, MB, Canada, R3E 3P5, and †Departments of Pediatrics and Communicable Diseases, Molecular ...

BACKGROUND Osseous injuries are a major facet of child abuse and in most patients radiographic imaging plays a major role in diagnosis. While some injuries are typically produced as a result of excessive and inappropriate force other injuries are nonspecific in terms of their causation, but become suspicious when the history provided by the caretakers is inconsistent with the type of injury pro...

Hypothalamus, the most evolutionary conserved regions of mammalian brain involved in maintaining homeostasis of life, integrates sensory and hormonal inputs and provides coordinated responses through motor outputs to key regulatory sites. The patterned outputs to various effector sites result in coordinated endocrine ,behavioral ,and autonomic responses to maintain the homeostasis. (1,2) Leptin...

BACKGROUND AND OBJECTIVES Changes in relative humidity, along with other meteorological factors, accompany ongoing climate change and play a significant role in weather-related health outcomes, particularly among children. The purpose of this review is to improve our understanding of the relationship between ambient humidity and child health, and to propose directions for future research. MET...

Vincenzo Belcastro *, Lucio Giordano , Dario Pruna , Cinzia Peruzzi , Francesco Madeddu , Patrizia Accorsi , Giuseppe Gobbi , Alberto Verrotti , Pasquale Striano g Neurology Unit, Department of Medicine, S. Anna Hospital, Como, Italy b Pediatric Neuropsychiatric Division, Spedali Civili, Brescia, Italy c Epilepsy Unit, Child Neuropsychiatry Department, University Hospital, Cagliari, Italy Depar...

During the past 35 years Oman has undergone a rapid socioeconomic and epidemiological transition leading to a steep reduction in child and adult mortality and morbidity due to the decline of various communicable diseases, including vaccine-preventable diseases. Good governance and planning, together with leadership and commitment by the government, has been a critical factor in this reduction. ...

1Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, Rua Jorge Viterbo Ferreira, no 228, 4050-313 Porto, Portugal 2Paediatric Gastroenterology Service, Department of Child and Adolescent, Centro Hospitalar do Porto, Largo Abel Salazar, 4099-001 Porto, Portugal 3Paediatric Service, Unidade Hospitalar de Famalicao, Centro Hospitalar do Médio Ave, Rua de Cupertino de Miranda, 476...

Introduction: This is a case of acute gonococcal conjunctivitis in 2.5 years old female child.
 Case: A child presented with redness, purulent and profuse discharge from left eye associated upper eyelid swelling. The culture conjunctival swab revealed Neisseria gonorrhoeae. was treated intravenous antibiotics fortified medications.
 Conclusion: Unlike young adults newborn (GCC), child...