Introduction: Patients with cleidocranial dysplasia commonly present with significant dental problems, such as retention of multiple deciduous teeth, impaction or delayed eruption of teeth and the presence of multiple Madhu P. Sivan1, Jayakumar K.2, Jayalakshmi P. S.3, N. Sruthi4 Affiliations: 1MDS, Provisional Lecturer, Department of Oral and Maxillofacial Surgery, Government Medical College, ...

Cleidocranial dysplasia (CCD) (MIM 119600) is an autosomal dominant skeletal dysplasia characterised by abnormal clavicles, patent sutures and fontanelles, supernumerary teeth, short stature, and a variety of other skeletal changes. The disease gene has been mapped to chromosome 6p21 within a region containing CBFA1, a member of the runt family of transcription factors. Mutations in the CBFA1 g...