Background As universal health coverage becomes the norm in many countries, it is important to determine public priorities regarding benefits to include in health insurance coverage. We report results of participation in a decision exercise among residents of Switzerland, a high-income country with a long history of universal health insurance and deliberative democracy.   Methods We adapted the...

Engineering software systems is a multidisciplinary activity, whereby a number of artifacts must be created — and maintained — synchronously. In this paper we investigate whether production code and the accompanying tests co-evolve by exploring a project’s versioning system, code coverage reports and size-metrics. Three open source case studies teach us that testing activities usually start lat...

We present a novel methodology for test case generation based on UML sequence diagrams. We create message dependence graphs (MDG) from UML sequence diagrams. Edge marking dynamic slicing method is applied on MDG to create slices. Based on the slice created with respect to each predicate on the sequence diagram, we generate test data. We formulate a test adequacy criterion named slice coverage c...

Testing is one of the very important component of software development process. Properly generated test sequences may not only locate the defects in software, but also help in reducing the high cost associated with software testing. It is often desired that test sequences should be automatically generated to achieve required test coverage. Automatic test sequence generation is a major problem i...

This document discusses data flow testing: a form of structural (white box) testing that is a variant on path testing, focussing on the definition and usage of variables, rather than the structure of the program. Two different topics relating to data flow testing are discussed: define/use testing, along with a set of test coverage metrics; and the concept of splitting a program into slices, acc...

MOTIVATION Investigators utilize gap estimates for DNA sequencing projects. Standard theories assume sequences are independently and identically distributed, leading to appreciable under-prediction of gaps. RESULTS Using a statistical scaling factor and data from 20 representative whole genome shotgun projects, we construct regression equations that relate coverage to a normalized gap measure...

Oncotype DX is recommended for coverage in early stage breast cancer when used to guide adjuvant chemotherapy treatment decisions for women who are lymph node negative (strong recommendation). The following genetic tests of cancer tissue are recommended for coverage (strong recommendation):  BRAF gene mutation testing for melanoma  Epidermal growth factor receptor (EGFR) gene mutation testing...

Software testing is a proven technique widely used to increase confidence that a software product behaves as expected and to gather system usage information to support evolution. Many structural coverage criteria techniques are used to perform and measure testing activities, but their complete satisfaction is rarely achieved resulting in code release with neglected test obligations. This paper ...