In the first decade of twenty-first century, CSIRO’s role broadened toward national mission-oriented research, less directly focused on supporting Australian industry. terms its legislated mandate, it deliberately placed increased emphasis ‘contributing to achievement objectives’ and ‘assisting industry’. This change was accompanied by an organisational restructuring with introduction a flagshi...

Mitogen-activated protein kinase (MAPK) pathways are implicated in several cellular processes including proliferation, differentiation, apoptosis, cell survival, cell motility, metabolism, stress response and inflammation. MAPK pathways transmit and convert a plethora of extracellular signals by three consecutive phosphorylation events involving a MAPK kinase kinase, a MAPK kinase, and a MAPK. ...

In this paper we address the design of a fuzzy flight controller that achieves stable and robust “aggressive” manoeuvrability for an unmanned helicopter. The fuzzy flight controller proposed consists of a combination of a fuzzy gain scheduler and linguistic (Mamdani-type) controller. The fuzzy gain scheduler is used for stable and robust altitude, roll, pitch, and yaw control. The linguistic co...

We have previously identified the suramin analog 4,4',4'',4'''-(carbonylbis(imino-5,1,3-benzenetriylbis(carbonylimino)))tetrakis-benzene-1,3-disulfonic acid (NF449) as a low nanomolar potency antagonist of recombinant P2X(1) receptors. Here, we characterize, by two-electrode voltage-clamp electrophysiology, three isomeric suramin analogs designated para-4,4',4'',4''''-(carbonylbis(imino-5,1,3-b...

Current Address: Bolton Fellow, CSIRO Australia Telescope National Facility, Cnr Vimiera & Pembroke Roads, Marsfield NSW 2122, Australia; email: [email protected] Packard Fellow Janksy Fellow