نتایج جستجو برای: csiro mk3
تعداد نتایج: 982 فیلتر نتایج به سال:
The objective of this study was to compare between measured weather data (2010-2019) and projected for the same period obtained from three global climate models (HadGEM2-ES, CSIRO-Mk3-6-0, MIROC5), with its four RCPs scenarios (RCP2.6, RCP4.5, RCP6.0 RCP8.5) developed five agro climatic zones Egypt determine most suitable scenario be used in each agro-climatic zone projection effect change futu...
Climate change effects on long-term groundwater (GW) resource developments in the Tana Basin, Ethiopia, are a growing concern. Efforts to provide estimates under various climatic uncertainties lacking region. To address this need, we deployed fine-resolution (500 m) GW model using MODFLOW-NWT for Upper Blue Nile The was calibrated based 98 historical instantaneous well-level measurements (RMSE ...
Zarrineh River is located in the northwest of Iran, providing more than 40% total inflow into Lake Urmia that one largest saltwater lakes on earth. a highly endangered ecosystem brink desiccation. This paper studied impacts climate change streamflow River. The was simulated and projected for period 1992–2050 through seven CMIP5 (coupled model intercomparison project phase 5) data series (namely...
استفاده از خروجی مدلهای گردش کلی جوّ - اقیانوس (AOGCMs) به‌منزلة معتبرترین ابزار در تحقیقات تغییر اقلیم، در حال افزایش است. تاکنون نسخه‌های گوناگونی از مدلهای AOGCM عرضه شده است که از آن جمله می‌توان به مدلهای اولین گزارش ارزیابی هیئت بین‌المللی تغییر اقلیم (IPCC) تحت عنوانFAR(1990) ، مدلهای دومین گزارش با عنوان SAR(1996)، مدلهای سومین گزارش با عنوان TAR(2001) و مدلهای چهارمین گزارش ارزی...
MK2 and MK3 represent protein kinases downstream of p38 mitogen-activated protein kinase (MAPK). Deletion of the MK2 gene in mice resulted in an impaired inflammatory response although MK3, which displays extensive structural similarities and identical functional properties in vitro, is still present. Here, we analyze tumor necrosis factor (TNF) production and expression of p38 MAPK and tristet...
Although the MK3 gene was originally found deleted in some cancers, it is highly expressed in others. The relevance of MK3 for oncogenesis is currently not clear. We recently reported that MK3 controls ERK activity via a negative feedback mechanism. This prompted us to investigate a potential role for MK3 in cell proliferation. We here show that overexpression of MK3 induces a proliferative arr...
The gammaherpesviruses characteristically drive the proliferation of latently infected lymphocytes. The murine gammaherpesvirus 68 (MHV-68) MK3 protein contributes to this process in vivo by evading CD8(+)-T-cell recognition during latency, as well as during lytic infection. We analyzed some of the molecular mechanisms that control MK3 expression. No dedicated MK3 mRNA was detected. Instead, th...
The liver plays an important role in innate and adaptive immunity and in particular in induction of tolerance. The liver is frequently exposed to pathogens like gutderived food antigens, environmental toxins and bacterial or viral products reaching the liver via the blood flow. It is central for production of acute phase proteins, among others including protease inhibitors, soluble patternrecog...
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