Lidocaine bears in its structure both an aromatic ring and a terminal amine, which can be protonated at physiological pH, linked by an amide group. Since lidocaine causes multiple inhibitory actions on nicotinic acetylcholine receptors (nAChRs), this work was aimed to determine the inhibitory effects of diethylamine (DEA), a small molecule resembling the hydrophilic moiety of lidocaine, on Torp...

This paper processes a combined method, based on VIKOR and Data Envelopment Analysis (DEA) to select the units with most efficiency. We utilize the VIKOR as compromise solution method. This research is a two-stage model designed to fully rank the alternatives, where each alternative has multiple inputs and outputs. The problem involves BELIEF parameters in the solution procedure. First, the alt...

Dear DEA [2] Description: This series of five clinical vignettes focuses on common concerns of clinicians and illustrates the relationship between the Drug Enforcement Administration (DEA) and health professionals, noting that the DEA can help explain federal regulations on legally prescribing controlled substances to patients. Authors: Heit HA, Covington E, Good PM. Source: Pain Medicine field...

In this work, the synthesis and characterization of functionalized platinum nanoparticles (PtNPs) have been investigated. PtNPs were obtained by a wet redox procedure using 2-diethylaminoethanethiol hydrochloride (DEA) as capping agent. By varying the Pt/thiol molar ratio, monodispersed and stable particles with diameters in the range of 3-40 nm were isolated. The amino functionality allows neu...

In performance evaluations, data without explicit inputs (such as index data, pure output data) are widely used. To directly use such data, this paper presents a study on building DEA models without explicit inputs,DEA-WEI models, in which convexity assumption is considered to be satisfied while the ratio data are constructed. Finally, an example of the modified DEA-WEI model is presented and c...

INTRODUCTION The anti-fibrotic hormone, relaxin, has been inferred to disrupt transforming growth factor (TGF)-β1/Smad2 phosphorylation (pSmad2) signal transduction and promote collagen-degrading gelatinase activity via a nitric oxide (NO)-dependent pathway. Here, we determined the extent to which NO, soluble guanylate cyclase (sGC) and cyclic guanosine monophosphate (cGMP) were directly involv...

In this paper, we present a recurrent neural network model for solving CCR Model in Data Envelopment Analysis (DEA). The proposed neural network model is derived from an unconstrained minimization problem. In the theoretical aspect, it is shown that the proposed neural network is stable in the sense of Lyapunov and globally convergent to the optimal solution of CCR model. The proposed model has...

OBJECTIVES This study examined how ethanolamines (EAs) with the same functional alcohol group (HOCH(2)CH(2)), such as mono-EA (MEA), di-EA (DEA), and tri-EA (TEA), in water-based metalworking fluids (wbMWFs) are vaporized, condensed, and transformed by heat generated during metalworking. METHODS Two types of experimental apparatus were manufactured to achieve these objectives. RESULTS Vapor...

DHA (docosahexaenoic acid, C22:6,n-3) has been shown to promote neurite growth and synaptogenesis in embryonic hippocampal neurons, supporting the importance of DHA known for hippocampus-related learning and memory function. In the present study, we demonstrate that DHA metabolism to DEA (N-docosahexaenoylethanolamide) is a significant mechanism for hippocampal neuronal development, contributin...

The conventional data envelopment analysis (DEA) assumes that the inputs and outputs are real values. However, in many real world instances, some inputs and outputs must be in integer values. While integer-valued DEA models have been proposed, the current paper develops an integer-valued DEA super-efficiency model. Super-efficiency DEA models are known to have the problem of infeasibility. Rece...