نتایج جستجو برای: dmd and me finally
تعداد نتایج: 16839224 فیلتر نتایج به سال:
The dystrophin deficiency leading to the severely progressing muscle degeneration in Duchenne muscular dystrophy (DMD) patients is caused by frame-shifting mutations in the DMD gene. We are developing a reading frame correction therapy aimed at the antisense-induced skipping of targeted exons from the pre-mRNA. Despite introducing a (larger) deletion, an in-frame transcript is generated that al...
Background and objectives: Otostegia persica (Labiatae) is an endemic plant of Iran and is used for its anti-inflammatory properties in folk medicine of Sistan and Baluchestan province. The aim of the present study was to investigate the anti-nociceptive and anti-inflammatory effects of O. Persica different fractions and identification of the natural compounds...
We present our study on flows past porous obstacles, which exhibit complex nonlinear dynamics. Regions in the near-wake host multiple modes of hydrodynamic instabilities, interact with bleed flow from trailing edge. As a result, developing shear layers weaken and wakes protract. The dynamics are largely altered by configuration patches even when plan porosities similar. describe wake turbulence...
Dystrophin (Dmd) is a structural protein that links the extracellular matrix to actin filaments in muscle fibers and is required for the maintenance of muscles integrity. Mutations in Dmd lead to muscular dystrophies in humans and other vertebrates. Here, we report the characterization of a zebrafish gene trap line that fluorescently labels the endogenous Dmd protein (Dmd-citrine, Gt(dmd-citrin...
the aim of the current study was to investigate the relationship among efl learners learning style preferences, use of language learning strategies, and autonomy. a total of 148 male and female learners, between the ages of 18 and 30, majoring in english literature and english translation at islamic azad university, central tehran were randomly selected. a package of three questionnaires was ad...
the present paper deals with criminal issues. for example, legal injunction on the necessity of returning a deposit has a legal nature and legal injunction on the punishment of those who breach the trust has a criminal nature. existing social issues are the basis of classification of some instances into the issue, some of which are based on variation and others on quality. therefore, the motiva...
تعیین کیفیت علوفه گونه های موجود در مراتع از مهمترین عواملی است که جهت محاسبه ظرفیت چرایی و مدیریت صحیح مراتع لازم و ضروریست. در این تحقیق کیفیت گونه گیاهیlibanoticum agropyron در سه مرحله فنولوژیک در دره نژ ارومیه مورد بررسی قرار گرفت. بعد از نمونهبرداری نمونهها به آزمایشگاه منتقل گردید. شاخصهای کیفی دیواره سلولی منهای همیسلولز (adf)، درصد ماده خشک قابل هضم (dmd)، انرژی متابولیسمی (me) و ...
BACKGROUND Exon skipping therapy is an emerging approach in Duchenne Muscular Dystrophy (DMD). Antisense oligonucleotides that induce skipping of exon 51, 44, 45, or 53 are currently being evaluated in clinical trials. These trials were designed on the basis of data available in general DMD population. OBJECTIVES Our objective was to compare the clinical and functional statuses of non-ambulan...
the present study is paid to the evaluation of the welfare program of the unemployment insurance in iran. the main purpose which was the main reason for performing this thesis, was the unemployment insurance plan’s challenges in iran such as financial problems of this plan, prolongation of the credit receipt for some insured people, unemployment slow exiting from the unemployment insurance fund...
تعیین کیفیت علوفه گونههای موجود در مراتع از مهمترین عواملی است که جهت محاسبه ظرفیت چرایی و مدیریت صحیح مراتع لازم و ضروریست. در این تحقیق کیفیت گونه گیاهیlibanoticum Agropyron در سه مرحله فنولوژیک در دره نژ ارومیه مورد بررسی قرار گرفت. بعد از نمونهبرداری نمونهها به آزمایشگاه منتقل گردید. شاخصهای کیفی دیواره سلولی منهای همیسلولز (ADF)، درصد ماده خشک قابل هضم (DMD)، انرژی متابولیسمی (ME) و ...
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