http://healthaffairs.org/blog/2011/06/08/rx-drug-shortages-regulation-can-be-deadly/ Cass Sunstein, President Obama’s regulatory czar, announced last week that the administration intends to repeal costincreasing, unnecessary regulations [1] from 30 different agencies. If the administration is serious in this effort, a good place to start is with a web of regulations that are preventing life sav...

Innovative regulatory and legislative measures to stimulate and facilitate the development of new antimicrobial drugs are needed. We discuss research approaches that can aid regulatory decision making on the treatment of resistant infections and minimization of resistance selection. We also outline current and future measures that regulatory agencies may employ to help control resistance and pr...

Victims of AIDS and other incurable diseases are denied access to potentially valuable experimental drugs by the U.S. Food and Drug Administration. Under the present law, no new drug or medical device can be sold until it has been approved as safe and effective" by the FDA. New-drug approval is an expensive process that routinely takes years to complete. Unapproved experimental products cannot ...

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Cellular growth, development, and differentiation are tightly controlled by a conserved biological mechanism: the cell cycle. This cycle is primarily regulated by cyclin-dependent kinase (CDK)-cyclin complexes, checkpoint kinases, and CDK inhibitors. Deregulation of the cell cycle is a hallmark of the transformation of normal cells into tumor cells. Given its importance in tumorigenesis, severa...

purpose: to compare early maladaptive schemas and coping styles in drug dependent and non-dependent prisoners of zahedan city.   materials and methods: this was an ex post facto study. the population of the study consisted of all men prisoners of zahedan prison in 2013. the participants were 240 prisoners among which 120 prisoners were selected by convenience sampling method and the rest by sim...