The phase-transition temperatures of an elastin-like polypeptide (ELP) with the (GVGVP)40 sequence and solvent dipolarity/polarizability, hydrogen-bond donor acidity, and hydrogen-bond acceptor basicity in its aqueous solutions were quantified in the absence and presence of different salts (Na2SO4, NaCl, NaClO4, and NaSCN) and various osmolytes (sucrose, sorbitol, trehalose, and trimethylamine ...

The "early-labeled" peak (ELP) of 14CO excretion following injection of glycine-2-14C was used to study erythropoiesis in a patient with sideroblastic anemia and in four subjects with myeloproliferative disorders. The ELP was greatly enlarged in all patients, as compared with a normal volunteer. The contour of the peaks from the hematologically abnormal subjects suggested the presence of increa...

The professional Electronic Leadership Portfolio (ELP) is an effective method for the promotion of Information and Communication Technology (ICT) in the educational arena, both as a model for aspiring leaders and as a model for the necessary development of skills in teachers. Furthermore, the ELP provides a framework for future measurement of leadership skills and development as well as providi...

This study aimed to analyze the determinants of short (ECP) and long-term (ELP) indebtedness companies in Public Utility sector Brazil, light pecking order trade-off theories. The methodology used was multiple regression analysis with panel data for period from 2008 2017, using ECP EPL as dependent variables; profitability, risk, size, current liquidity index, growth tangibility independent var...

Achieving sustainability is a major objective of Saudi Arabia’s Vision 2030. This study investigates one Ministry Education initiative to achieve through the establishment its Optimum Utilisation Teaching Staff Programme (OUTSP). The focuses in particular on OUTSP’s two-term English Language (ELP). First, it details ELP’s modules; then, analyses overall results for 170 431 candidates who joined...

Elastin-like polypeptides are biopolymers composed of the pentapeptide repeat Val-Pro-Gly-Xaa-Gly. Elastin-like polypeptides are soluble in aqueous solution below their transition temperature, but they hydrophobically collapse and aggregate when the temperature is raised above the transition temperature. Previous studies have suggested that the aggregation of these polypeptides in response to e...

The modulation of the lower critical solution temperature (LCST) of two elastin-like polypeptides (ELPs) was investigated in the presence of 11 sodium salts that span the Hofmeister series for anions. It was found that the hydrophobic collapse/aggregation of these ELPs generally followed the series. Specifically, kosmotropic anions decreased the LCST by polarizing interfacial water molecules in...

BACKGROUND Plants are recognized as an efficient and inexpensive system to produce valuable recombinant proteins. Two different strategies have been commonly used for the expression of recombinant proteins in plants: transient expression mediated by Agrobacterium; or stable transformation of the plant genome. However, the use of plants as bioreactors still faces two main limitations: low accumu...

A combination of Fourier transform infrared and phase transition measurements as well as molecular computer simulations, and thermodynamic modeling were performed to probe the mechanisms by which guanidinium (Gnd+) salts influence the stability of the collapsed versus uncollapsed state of an elastin-like polypeptide (ELP), an uncharged thermoresponsive polymer. We found that the cation's action...

En la actualidad algunas de las neoplasias hematológicas, entre ellas gammapatías monoclonales (GM) son incurables a pesar los avances en terapias oncológicas. Los estudios GM Ecuador escasos; últimas estadísticas se muestra que el mieloma múltiple (MM) encuentra primeros 25 tumores país. Las pruebas diagnóstico más utilizadas electroforesis y cadenas ligeras Con objetivo caracterizar resultado...