BACKGROUND AND AIMS The relationship between Helicobacter pylori infection and gastro-oesophageal reflux disease (GORD) is controversial but it is accepted that GORD is associated with increased exposure to gastric acidity. The proinflammatory interleukin (IL)-1B polymorphisms increase the risk of hypochlorhydria and gastric atrophy. We examined the association between proinflammatory cytokine ...

INTRODUCTION Anti-cyclic citrullinated peptide autoantibodies (anti-CCP) are the most specific serologic marker for rheumatoid arthritis (RA). Genetic polymorphisms in a citrullinating (or deiminating) enzyme, peptidyl arginine deiminase type IV (PADI4) have been reproducibly associated with RA susceptibility in several populations. We investigated whether PADI4 polymorphisms contribute to anti...

Erosive pustular dermatosis of the scalp is a rare inflammatory skin disorder that most commonly affects elderly with androgenic alopecia. It characterized by painless crusted erosions usually appear following traumatic event. has been associated several autoimmune diseases and responds to high-potency topical steroids. This report presents case erosive in an 84-year-old man who presented our c...

The lichen planus is a mucocutaneous disease with unknown etiology and auto-immune pathogenia. There have been three variants of lichen planus: the reticular, the plaque-like and the atrophic-erosive lesions. It s a chronic disease with acute relapses that generally affects more frequently to women from the fourties. The diagnostic is based on the clinic identification of the lesions joined wit...

Oral Lichen Planus is a chronic inflammatory disease of unknown etiology. Erosive/ ulcerative oral lichen planus is often a painful condition that tends to become malignant, urging appropriate therapy. Laser therapy has recently been suggested as a new treatment option without significant side effects. This article presents two cases of erosive/ ulcerative oral lichen planus, who had not receiv...

Oral lichen Planus(OLP) is a chronic mucocutaneous autoimmune disease that mostly affects middle-aged females. Various factors including psychological stress , drugs and various systemic conditions has been linked to the etiopathogenesis of OLP. It has got several variants including reticular, erosive, atrophic and ulcerative-types. Erosive and atrophic variants have been most often linked to i...